Current Pharmacological Treatment of Dementia

Treatment of Dementia - The Carlat Psychiatry Report (TCPR)

Patients with dementia and their families may express frustration about the limited number of options for improving cognitive symptoms, but they are not without choices. Here we will review a number of pharmacological treatment options for Alzheimer’s disease (AD) and other major types of dementia.

Medications for Treating Alzheimer’s Dementia

The Diagnosis and Treatment of Dementia

While drug companies have been working hard to come up with new options for the treatment of dementia, there have been no new FDA approvals since memantine (Namenda) hit the scene in 2003.

Research Update

Off-Label Use of Antipsychotics Effective for Some Indications

Over the past decade or so, atypical antipsychotic use has exploded, for both FDA approved indications and off-label treatments. A recent meta-analysis examined the efficacy (when compared to placebo), comparative effectiveness (when compared to another medication), and safety of atypicals.

SNRIs Likely No Better than SSRIs for Depression

Due to their inhibition of both serotonin and norepinephrine reuptake, the SNRIs venlafaxine (Effexor) and duloxetine (Cymbalta) have been billed as possessing an advantage over SSRIs.