Mood Stabilizers


Nuedexta for Pseudobulbar Affect

Nuedexta is a combination of dextromethorphan (DM) and quinidine sulfate. You might reasonably ask why these two agents would have ever been considered as a treatment for PBA.

The Carlat Guide to Medications Used for Insomnia

This handy table lists the medications most often used to treat insomnia.

Sleeping Pills: Which Ones for Which Patients? [Subscribers Only]


Insomnia is one of the most common comorbidities you’ll see in your depressed and anxious patients. But it is often misunderstood. While the common view is that insomnia is caused by a primary psychiatric or medical condition, it is more accurate to simply say that patients have insomnia and depression at the same time. Insomnia is almost never an isolated problem.

Research Update

Mood Stabilizer plus Antidepressant May Protect Against Mania

Most of you would hesitate to put a patient with bipolar I on antidepressants without adding a mood stabilizer, in order to prevent a switch to mania. If this is your clinical practice, you are following the recommendations of the APA consensus guidelines for the treatment of bipolar depression. But the hard data to support the danger of switching is surprisingly weak.

Expert QA

Complementary and Alternative Medicine for Mood Disorders

Defining CAM is challenging. One of the things that makes it so hard to have a concrete discussion on CAM is that it means different things to different people.