The field of smoking cessation has been abuzz since the FDA approved Chantix (varenicline) in 2006. Pfizer’s studies showed better efficacy for Chantix than bupropion (Wellbutrin/Zyban), and the mechanism of action is fascinating. But several controversial issues have arisen to muddy the waters. Reports of psychiatric side effects surfaced, prompting the FDA to issue a public health advisory. And on an unrelated note, a new “cold turkey” quit smoking movement has arisen, filled with critics of pharmacological cures. Let’s look at some of these issues in more detail.
Purchase a subscription
To view the full content, you need to purchase a subscription.
Deputy Editor: Talia Puzantian, PharmD, BCPP, clinical psychopharmacology consultant in private practice in Los Angeles, CA
Executive Editor:Janice Jutras
Ronald C. Albucher, MD, is the director of counseling and psychological services and clinical assistant professor of psychiatry, Stanford University in Palo Alto, CA.
Steve Balt, MD is a psychiatrist in private practice in the San Francisco Bay area.
Richard Gardiner, MD, is a psychiatrist in private practice in Potter Valley, CA.
Alan D. Lyman, MD, is a child and adolescent psychiatrist in private practice in New York City, NY.
James Megna, MD, PhD, is the director of inpatient psychiatry and an associate professor of psychiatry and medicine at SUNY Upstate Medical University in Syracuse, NY.
Robert L. Mick, MD, is a contract physician in addiction medicine and military psychiatry in Bloomfield, NY.
Michael Posternak, MD, is a psychiatrist in private practice in Boston, MA.
Glen Spielmans, PhD, is an assistant professor of psychology at Metropolitan State University in St. Paul, MN.
Marcia L. Zuckerman, MD is director of Psychiatric Services at Walden Behavioral Care in Waltham, MA.
All editorial content is peer reviewed by the editorial board. Dr. Albucher, Dr. Balt, Dr. Gardiner, Dr. Goldberg, Dr. Lyman, Dr. Megna, Dr. Mick, Dr. Posternak, Dr. Spielmans, and Dr. Zuckerman have disclosed that they have no relevant financial or other interests in any commercial companies pertaining to this educational activity. Dr. Balt discloses that his spouse is employed as a sales representative for Otsuka America, Inc.