We look at three ways that the body influences psychiatric disorders in the brain – through neurohormones, inflammation, and metabolic health. Dr. Rodrigo Mansur delves into that last one in our expert interview, and we end with a new app...

Around 50 controlled trials have tested benzodiazepines in depression, and the results are surprising. They seem to work. In this episode we look at the controversies surrounding this research and what it means for practice. Published On: 4/5/2021 Duration: 25...

Overdose deaths have been rising during COVID, but simply stopping the drug causes problems of its own. In this episde, Ashwin Patkar and Richard Weisler discuss how to reduce the risk of opioid deaths in psychiatric patients. Their Current Psychiatry...

Swapnil Gupta, author of Deprescribing in Psychiatry, shares tips on how to help patients taper off benzodiazepines and psychostimulants. She adds a special therapeutic ingredient, but it’s not a medication. Then we digress into one of the oldest medications known...

DSM-5 has adopted many of the concepts from Hagop Akiskal’s Bipolar Spectrum, but not in the way he had planned. Here we trace his thinking back to the early 1970’s, when Dr. Akiskal reshaped the way we think about depression...

What works best when the first antidepressant fails? And the second? Today, we bring you part 1 in our special series on treatment resistant depression. Published On: 3/7/21 Duration: 16 minutes, 1 second Published On: 3/7/21 Duration: 16 minutes, 1 second Transcript:...

For nearly 17 years, since the FDA black box warning about suicidality with antidepressants, our community has been quoting data that downplays this concern. We were wrong. We were deceived. Antidepressants can be lifesaving, but there really is a duty...

In 2012, psychiatrists at Harvard’s Massachusetts General Hospital discovered a novel antidepressant. It seemed to improve depression and cognition without causing any significant side effects. There was only one problem. The ingredients were practically free, and there was no way...

Bupropion and restless legs syndrome: a randomized controlled trialWhen a patient complains that their mood got worse on an antidepressant, it doesn’t necessarily mean they are sensitive to medications. In this episode, we detail 6 other reasons why depression can...

An interview with Swapnil Gupta on when and how to come off psychiatric medications. Plus, tips on cross-tapering antidepressants, and the word of the day: Ephedra. Published On: 2/8/2021 Duration: 17 minutes, 1 second Transcript: Today, an interview with Swapnil Gupta on...