Clear, engaging, and practical updates on clinical psychiatry.

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Episodes

A Therapy to Prevent Depression

July 12, 2021 | Podcasts

Antidepressants get people better from depression, but what keeps them better? In this episode, Dr. Giovanni Fava suggests we may need to stop trying to stamp-out pathology and start finding ways to enhance well-being as patients recover. Published On: 7/12/2021...

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The Bright Side of the Serotonin Gene

July 5, 2021 | Podcasts

We interview Vladimir Maletic about the serotonin transporter gene (SERT). It’s supposed to make people more vulnerable to depression, but there’s a bright side to this gene that rarely gets attention. We talk about the strengths it confers, and whether...

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The Rediscovery of Disulfiram

June 28, 2021 | Podcasts

New analyses rank disulfiram (Antabuse) among the most effective medications for alcohol use disorders. But why is it so underutilized? In this podcast we explore the history of this therapy – the oldest medication that is still in use in...

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Viloxazine (Qelbree): A Faster Strattera?

June 20, 2021 | Podcasts

On April 2, 2021, viloxazine, brand name Qelbree, received FDA approval for the treatment of ADHD in children and adolescents ages 6-17 years old. The latest issue of The Carlat Child Psychiatry Report includes a News of Note covering this newly approved...

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Pharmacogenetics: Not Quite Ready for Prime Time?

June 7, 2021 | Podcasts

Clinicians are inundated with ads for genetic testing, but is genetic testing currently helpful for informing clinical care? The latest issue of The Carlat Child Psychiatry Report includes an interview with Dr. Aaron Besterman, who’s an adult and child & adolescent...

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Bipolar, Barbiturates, and Punk Rock

May 31, 2021 | Podcasts

Brian Wilson, Lou Reed, and Ian Curtis all created new music genres, and each of them is reputed to have had bipolar disorder. We look at the evidence behind that, and learn a few things about psychiatry and creativity along...

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How COVID Affects the Brain

May 24, 2021 | Podcasts

The psychiatric syndromes caused by COVID infection may look like commonplace DSM-5 disorders, but the cause and treatment may be different. Reference: Boldrini M, Canoll PD, Klein RS. How COVID-19 Affects the Brain. JAMA Psychiatry. 2021 Mar 26. Published On: 5/24/2021...

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13 Ways to Use Topiramate

May 17, 2021 | Podcasts

We ask the big questions: Is topiramate a drug or a sugar? Do you need to use the FDA-approved combo pill for weight loss? And which of its 13 off-label psychiatric uses are ready for clinical practice? Published On: 5/17/2021...

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Can Eszopiclone Augment Antidepressants?

April 26, 2021 | Podcasts

We unpack 6 studies of the hypnotic eszopiclone in depressive and anxiety disorders, and conclude that there’s more going on here than a simple benefit in sleep. Our word of the day tells us something about what’s missing in depression:...

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