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Depression Episodes

How to Treat Untreatable Depression

July 13, 2020 | Podcasts

Joseph Goldberg, MD shares his top psychopharm strategies for highly-treatment resistant depression, and weighs in on whether further medication trials are ever futile. Published On: 7/13/2020 Duration: 15 minutes, 46 seconds Related Articles: "When Further Medication Trials Seem Futile," The Carlat Psychiatry Report, June/July 2020


A New Cause of Depression: Light at Night [60 Sec Psych]

June 24, 2020 | Podcasts

Evening light is associated with so many health risks ─ cancer, diabetes, heart disease ─ that the AMA has a position statement on it. Psychiatrists may need to pay attention as well. It’s been linked to depression, mania, and poor cognition in epidemiologic studies, and this animal study confirms that. An K, Zhao H, Miao Y, et al. A circadian


The Strongest Meds for Treatment Resistant Depression [60 Sec Psych]

June 24, 2020 | Podcasts

Lithium, atypical antipsychotics, ketamine, thyroid… these consistently rank among the most effective medications for treatment resistant depression, but which is the strongest? Strawbridge R, Carter B, Marwood L, et al. Augmentation therapies for treatment-resistant depression: systematic review and meta-analysis. Br J Psychiatry. 2019;214(1):42


Who Will Get Cognitive Decline? [60 Sec Psych]

June 23, 2020 | Podcasts

The brain changes that lead to dementia can be seen as early as 25 years before the illness starts. We can’t test for those changes, but who might be at risk? This meta-analysis led by Carol Hudon looked at studies that followed healthy middle aged adults with no cognitive problems to see which behavioral and psychological factors predicted dement


Which to Treat First: Depression or Anxiety? [60 Sec Psych]

June 19, 2020 | Podcasts

This month Dr. Jan Spiker and colleagues from Amserdam published an editorial on how to approach comorbid depression and anxiety. They base their suggestions on two recent meta-analyses that found comorbid symptoms decreased when the more clinically significant disorder was treated. Spijker J, Muntingh A, Batelaan N. Advice for Clinicians on How to T


Research Theme Park: Foodland

May 25, 2020 | Podcasts

Blueberries, walnuts, tea, salt, and the Mediterranean diet are featured in this playful but practical stroll through the latest research on food and the brain. Published On: 5/25/20 Duration: 10 minutes, 1 seconds Diet for Depression: Vegetables (5 servings per day), fruits (2–3 per day), wholegrain cereals (3 per day), protein (lean me


All the Meds for Bipolar Depression [60 Sec Psych]

May 23, 2020 | Podcasts

A new meta-analysis ranked all the medications for bipolar depression, and we found a surprise in the stack. A review of Bahji A, Ermacora D, Stephenson C, Hawken ER, Vazquez G. Comparative efficacy and tolerability of pharmacological treatments for the treatment of acute bipolar depression: A systematic review and network meta-analysis. J Affect Di


An Antidepressant Diet With Felice Jacka, MD

June 3, 2019 | Podcasts

A healthy diet is associated with an approximately 30% reduction in the risk for depression and a 40% improvement in cognition. That’s after controlling for education, income, other health behaviors, and body weight. This podcast discusses a recent interview with Felice Jacka, MD, Professor at Deakin University, Geelong, Victoria, Australia. She i