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Depression Episodes

Air Quality and Mental Health

September 16, 2020 | Podcasts

Air pollution, including particulate matter from forest fires, is a leading cause of health problems globally. It is also linked to psychiatric problems in children and adolescents. We take a closer look at the evidence and clinical implications in this episode. Published On: 9/17/2020 Duration: 14 minutes, 51 seconds Related Article: "Air


How to Minimize Lithium's Side Effects

September 7, 2020 | Podcasts

Nausea, tremor, cognition, and renal function. We bring you our top tips for managing these side effects, including when to use instant release vs. controlled release and how to optimize the serum level for patient safety. Published On: 9/7/2020 Duration: 20 minutes, 30 seconds Transcript: Lithium. The word conjures up thoughts of toxicity, danger


A Landmark Adoption Study [60 Sec Psych]

September 2, 2020 | Podcasts

Dr. Kenneth Kendler's latest compares biological siblings where one was adopted and the other raised by the birth parents. The study found that children adopted into a stable adoptive home had a reduced rate of depression by 23%. [Link] Published On: 9/2/2020 Duration: 2 minutes, 4 seconds Transcript: Over the past 40 years Dr. Ken Kendl


Existential Despair and Bipolar Depression

August 31, 2020 | Podcasts

Nassir Ghaemi reads excerpts from his work on the therapeutic relationship in bipolar disorder. We talk about how to empathize with manic patients through the technique of “manic siding,” and catalogue over a dozen types of bipolar depression, including one that Dr. Ghaemi calls “existential despair.” [Link] Published On: 8/31/2020 Dur


Depressed and Indecisive [60 Sec Psych]

August 15, 2020 | Podcasts

Today’s study looked at psychological factors that predict relapse into depression. They people who were recovered from depression and taking antidepressants along with healthy controls, nearly 200 in total. All the underwent a decision making test that asked them to exert effort─a button pressing task─to get rewards. The antidepressants we


The Best SSRI - Part 1

July 27, 2020 | Podcasts

We search through the rubble of 1990's marketing to find out what makes the SSRIs different, and encounter along the way our word of the day: Zimelidine. Published On: 7/27/20 Duration: 10 minutes, 47 seconds Transcript: From the quest for the holy grail to the meaning of dreams, humankind has always had a thirst for unanswerable ques


How to Treat Untreatable Depression

July 13, 2020 | Podcasts

Joseph Goldberg, MD shares his top psychopharm strategies for highly-treatment resistant depression, and weighs in on whether further medication trials are ever futile. Published On: 7/13/2020 Duration: 15 minutes, 46 seconds Related Articles: "When Further Medication Trials Seem Futile," The Carlat Psychiatry Report, June/July 2020


A New Cause of Depression: Light at Night [60 Sec Psych]

June 24, 2020 | Podcasts

Evening light is associated with so many health risks ─ cancer, diabetes, heart disease ─ that the AMA has a position statement on it. Psychiatrists may need to pay attention as well. It’s been linked to depression, mania, and poor cognition in epidemiologic studies, and this animal study confirms that. An K, Zhao H, Miao Y, et al. A circadian


The Strongest Meds for Treatment Resistant Depression [60 Sec Psych]

June 24, 2020 | Podcasts

Lithium, atypical antipsychotics, ketamine, thyroid… these consistently rank among the most effective medications for treatment resistant depression, but which is the strongest? Strawbridge R, Carter B, Marwood L, et al. Augmentation therapies for treatment-resistant depression: systematic review and meta-analysis. Br J Psychiatry. 2019;214(1):42


Who Will Get Cognitive Decline? [60 Sec Psych]

June 23, 2020 | Podcasts

The brain changes that lead to dementia can be seen as early as 25 years before the illness starts. We can’t test for those changes, but who might be at risk? This meta-analysis led by Carol Hudon looked at studies that followed healthy middle aged adults with no cognitive problems to see which behavioral and psychological factors predicted dement