We ask the big questions: Is topiramate a drug or a sugar? Do you need to use the FDA-approved combo pill for weight loss? And which of its 13 off-label psychiatric uses are ready for clinical practice? Published On: 5/17/2021...

A new study looked at what works best after two antidepressants have failed, and it claims to have found some surprising winners. We take a closer look at the data in the final episode of our two-part series on treatment...

We unpack 6 studies of the hypnotic eszopiclone in depressive and anxiety disorders, and conclude that there’s more going on here than a simple benefit in sleep. Our word of the day tells us something about what’s missing in depression:...

18 experts weigh in on how they use antidepressants in bipolar II. Sleep onset latency is defined, and we uncover the neuropsychiatric effects of marijuana in adults. Published On: 4/19/2020 Duration: 28 minutes, 11 seconds Transcript: Today, 18 experts weigh in on...

We look at three ways that the body influences psychiatric disorders in the brain – through neurohormones, inflammation, and metabolic health. Dr. Rodrigo Mansur delves into that last one in our expert interview, and we end with a new app...

Around 50 controlled trials have tested benzodiazepines in depression, and the results are surprising. They seem to work. In this episode we look at the controversies surrounding this research and what it means for practice. Published On: 4/5/2021 Duration: 25...

Overdose deaths have been rising during COVID, but simply stopping the drug causes problems of its own. In this episde, Ashwin Patkar and Richard Weisler discuss how to reduce the risk of opioid deaths in psychiatric patients. Their Current Psychiatry...

Swapnil Gupta, author of Deprescribing in Psychiatry, shares tips on how to help patients taper off benzodiazepines and psychostimulants. She adds a special therapeutic ingredient, but it’s not a medication. Then we digress into one of the oldest medications known...

DSM-5 has adopted many of the concepts from Hagop Akiskal’s Bipolar Spectrum, but not in the way he had planned. Here we trace his thinking back to the early 1970’s, when Dr. Akiskal reshaped the way we think about depression...

What works best when the first antidepressant fails? And the second? Today, we bring you part 1 in our special series on treatment resistant depression. Published On: 3/7/21 Duration: 16 minutes, 1 second Published On: 3/7/21 Duration: 16 minutes, 1 second Transcript:...