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Pharmacology Episodes

Living Well with Lithium

October 5, 2020 | Podcasts

A special edition for patients. Lithium is one of the most effective medications for bipolar and depression, but many of its marvels have remained obscure. Lithium has never benefited from a pharmaceutical ad (because it’s a mineral, not a medicine), so we’ve stepped in to fill that gap. Published On: 10/5/20 Duration: 23 minutes, 53 seconds Ro


Suvorexant prevents delirium [60 Sec Psych]

September 19, 2020 | Podcasts

We often worry about sleep meds in the medically ill, and there’s plenty of cause to: falls, respiratory suppression, and confusion. On the other hand, sleep disruption is a major risk factor for delirium, and there’s growing evidence that some sleep meds – ramelteon, melatonin, but not the benzos or z-hypnotics -  can prevent this sequale of s


How to Talk to Patients with Delusions

September 14, 2020 | Podcasts

Do antipsychotics treat all psychoses? And how do you talk to patients when they don’t work? Psychiatrist Michael Posternak shares his top tips. Plus: What the “Beads Task” tells us about the psychological underpinnings of delusional disorder. Published On: 9/13/2020 Duration: 15 minutes, 47 seconds Partial Transcript: Kellie: The one thin


Traumatic Brain Injury: An Interview with Jonathan Silver

August 17, 2020 | Podcasts

Traumatic Brain Injury (TBI) causes a host of psychiatric symptoms, and they don’t always respond to medications the way that other diagnoses do. In this interview, Jonathan Silver shares his top treatment tips on TBI. Dr. Silver is the co-editor of the APA’s the Textbook of Traumatic Brain Injury. Date Published: 8/17/2020 Duration: 15 minu


The Best SSRI - Part 2

August 2, 2020 | Podcasts

Are the SSRIs really that different? If a patient doesn't respond to one will they respond to another? We sift through three decades of research to find answers. Published On: 8/3/20 Duration: 19 minutes, 13 seconds Transcript:  Tony Soprano: “Here we go, here comes the Prozac” Welcome to the Carlat Psychiatry Podcast, keeping ps


Which Medications Should You Stop Before ECT? [60 Sec Psych]

August 1, 2020 | Podcasts

Electroconvulsive therapy (ECT) depends on the seizure threshold, so you don’t want to throw that off before starting it. Anticonvulsants and benzodiazepines are concerning, as are antidepressants. Although bupropion has a notorious risk for seizures, a recent meta-analysis of all antidepressants found buproprion’s risk was about average with the


Here’s What Happens When You Treat ADHD in the Elderly [60 Sec Psych]

July 15, 2020 | Podcasts

In 2004 the FDA approved the first stimulant for adult ADHD: Adderall XR. Now it’s nearly 20 years later, and some of those patients are elderly. Yet there are only a few studies of stimulants in people over age 50 ─ yes that’s the medical definition of elderly these days ─ and they are limited to case reports and patient surveys. [Link] Publ


Celebrex for Bipolar Depression

July 1, 2020 | Podcasts

This week we’re podcasting from the International Society for Bipolar Disorders 2020 conference, where we’ve been scouring the virtual halls for all that is practical and newsworthy. The yield is high so tune in for a new episode every day. Today, new results on an anti-inflammatory medication in bipolar depression. Published On: 7/1/2020 Durat


Will the Best Atypical Stand Up?

June 29, 2020 | Podcasts

Daily dispatches from the International Bipolar Disorders Conference. There are four atypical antipsychotics that treat bipolar depression, but which have the best balance of efficacy and tolerability? Published On: 6/29/2020 Duration: 5 minutes, 15 seconds Transcript: Will the Best Atypical Stand Up? This week we’re podcasting from


The Stats on a Dayvigo: A New Hypnotic [60 Sec Psych]

June 27, 2020 | Podcasts

Lemborexant/Dayvigo is the second in sleep med to join the orexin receptor antagonist family. It’s now on the pharmacy shelves, where it sits beside Suvorexant/Bellsomra, released in 2015. Landry I, Nakai K, Ferry J, et al. Pharmacokinetics, pharmacodynamics, and safety of the dual orexin receptor antagonist lemborexant: Findings from single-dose a