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Psychopharmacology Episodes

Celebrex for Bipolar Depression

July 1, 2020 | Podcasts

This week we’re podcasting from the International Society for Bipolar Disorders 2020 conference, where we’ve been scouring the virtual halls for all that is practical and newsworthy. The yield is high so tune in for a new episode every day. Today, new results on an anti-inflammatory medication in bipolar depression. Published On: 7/1/2020 Durat

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Will the Best Atypical Stand Up?

June 29, 2020 | Podcasts

Daily dispatches from the International Bipolar Disorders Conference. There are four atypical antipsychotics that treat bipolar depression, but which have the best balance of efficacy and tolerability? Published On: 6/29/2020 Duration: 5 minutes, 15 seconds Transcript: Will the Best Atypical Stand Up? This week we’re podcasting from

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The Strongest Meds for Treatment Resistant Depression [60 Sec Psych]

June 24, 2020 | Podcasts

Lithium, atypical antipsychotics, ketamine, thyroid… these consistently rank among the most effective medications for treatment resistant depression, but which is the strongest? Strawbridge R, Carter B, Marwood L, et al. Augmentation therapies for treatment-resistant depression: systematic review and meta-analysis. Br J Psychiatry. 2019;214(1):42

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3 Signs of Deviant Benzo Prescribing [60 Sec Psych]

June 20, 2020 | Podcasts

A group of French psychiatrists released two papers this month that looked into how often physicians prescribe benzodiazepines and hypnotics in ways that deviate from the guidelines. The result: 20-30% of these prescriptions deviated, and the rate was even higher in chronic medical and psychiatric disorders: 45-68%. But what I found most useful in the

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Can You Stop the Thyroid Med after Stopping Lithium? [60 Sec Psych]

June 17, 2020 | Podcasts

Hypothyrodism is fairly common on lithium, affecting about 14-17% of patients. Subclinical hypothyroidism is twice as common, and the risk is greater in the elderly. We know what to do about it ─ start thyroid supplement ─ but what hasn’t been clear is whether we should continue that supplement if lithium is stopped. Lieber I, Ott M, Öhlund L, et

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Trintellix for Negative Symptoms of Schizophrenia [60 Sec Psych]

June 16, 2020 | Podcasts

Negative symptoms are the main cause of disability in schizophrenia, and they’ve long been considered untreatable or barely treatable. This study looked at the antidepressant vortioxetine (Trintellix) for them. Vortioxetine is the only antidepressant that has cognitive benefits that they FDA allowed mention of in the prescribing information. The in

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Ambien in Older Adults: The Risks [60 Sec Psych]

June 13, 2020 | Podcasts

1 out of 3 zolpidem ─ Ambien ─ tablets are dispensed to older adults, but how safe and effective is it in the elderly? This review by Flavio Machado and colleagues pulled together 32 studies – half of which were randomized placebo-controlled trials ─ to look for answers. Study referenced: Machado FV, Louzada LL, Cross NE, Camargos EF, Dan

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Ambien in Older Adults: The Benefits [60 Sec Psych]

June 12, 2020 | Podcasts

1 out of 3 zolpidem ─ Ambien ─ tablets are dispensed to older adults, but how safe and effective is it in the elderly? This review by Flavio Machado and colleagues pulled together 32 studies – half of which were randomized placebo-controlled trials ─ to look for answers. Study referenced: Machado FV, Louzada LL, Cross NE, Camargos EF, D

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Meds for Anorexia [60 Sec Psych]

June 3, 2020 | Podcasts

People with anorexia usually don’t want to take medications, but does pharmacotherapy even work? Not at all, concludes Emanuele Cassioli and colleagues in this new meta-analysis. [Link] Published On: 6/2/2020 Duration: 1 minute, 51 seconds Transcript: People with anorexia usually don’t want to take medications, but does pharmacothera

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Antidepressants in Bipolar [60 Sec Psych]

May 28, 2020 | Podcasts

Do they help? Do they harm? And can mood stabilizers protect patients who take them? A review of Bahji A, Ermacora D, Stephenson C, Hawken ER, Vazquez G. Comparative efficacy and tolerability of pharmacological treatments for the treatment of acute bipolar depression: A systematic review and network meta-analysis. J Affect Disord. 2020;269:154‐184.

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