https://www.thecarlatreport.com/rss en-us Can brain stimulation help preserve function in Alzheimer’s disease? A year-long randomized trial suggests that PC- rTMS modestly slows cognitive and functional decline, offering a potential nonpharmacologic adjunct as clinicians seek alternatives to long-term medication burden.

]]> http://www.thecarlatreport.com/articles/5873 Mon, 23 Feb 2026 20:09:54 -0500 https://www.thecarlatreport.com/articles/5873-stimulating-the-precuneus-may-slow-alzheimers-decline Donepezil is the cholinesterase inhibitor with the longest track record and with which we have the most experience. It is generally considered the first-line agent for dementia. Though not a cure, it delays dementia progression by six to 12 months.

]]> http://www.thecarlatreport.com/articles/5025 Thu, 01 Jan 2026 13:11:35 -0500 https://www.thecarlatreport.com/articles/5025-donepezil-aricept-adlarity-fact-sheet-g Galantamine has no appreciable benefit over donepezil; however, its availability in a liquid formulation is helpful for patients who have difficulty swallowing pills.

]]> http://www.thecarlatreport.com/articles/5026 Thu, 01 Jan 2026 13:10:07 -0500 https://www.thecarlatreport.com/articles/5026-galantamine-razadyne-razadyne-er-fact-sheet-g Antipsychotics can reduce severe agitation or psychosis in dementia but at significant cost. Learn when to use them.

]]> http://www.thecarlatreport.com/articles/5877 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5877-prescribing-antipsychotics-for-neuropsychiatric-symptoms-in-dementia CGPR_Deprescribing_JanFebMar2026.jpg Stopping psychiatric medications can be harder than starting them. Dr. Mark Horowitz explains why withdrawal happens, how hyperbolic tapers work, and how to deprescribe safely while maintaining stability and trust.

]]> http://www.thecarlatreport.com/articles/5876 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5876-clinical-pearls-for-hyperbolic-tapering-of-psychiatric-medications-in-older-adults CGPR_JanFebMar 2026 QA1_Mark Horowitz_photo_sm.png Not all late-life low mood requires medication. This article explores how apathy differs from depression and how behavioral activation, microgoals, and lifestyle interventions can restore motivation, improve cognition, and reduce unnecessary antidepressant exposure in older adults.

]]> http://www.thecarlatreport.com/articles/5875 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5875-behavioral-strategies-for-apathy-and-late-life-depression Lithium remains a powerful mood stabilizer in late life, but aging kidneys change the equation. Dr. Michael Gitlin reviews kidney-conscious dosing, monitoring by eGFR, and shared decision-making strategies to balance lithium’s benefits against renal risk in older adults.

]]> http://www.thecarlatreport.com/articles/5874 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5874-using-lithium-in-older-adults-with-chronic-kidney-disease Jaime A.B. Wilson, PhD, ABN, ABPP, MSCP. Dr. Wilson has no financial relationships with companies related to this material. 

]]> http://www.thecarlatreport.com/articles/5872 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5872-olive-oil-linked-to-lower-dementia-mortality There is no cure for major neurocognitive disorder (MND), but several medications mitigate the progression of cognitive and functional decline.

]]> http://www.thecarlatreport.com/articles/5202 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5202-major-neurocognitive-disorder-medication-treatment Memantine’s indication (moderate to severe dementia only) may limit its use, but it does boast a unique mechanism of action and has some data to support its usefulness as an augmenter of donepezil.

]]> http://www.thecarlatreport.com/articles/5028 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5028-memantine-namenda-namenda-xr-fact-sheet-g Dementia Treatment Algorithm

]]> http://www.thecarlatreport.com/articles/6023 Wed, 31 Dec 2025 23:00:00 -0500 https://www.thecarlatreport.com/articles/6023-dementia-treatment-algorithm Psychiatry Practice Boosters, Fifth Edition (2026) - 4 SA / 10 CME Course

]]> http://www.thecarlatreport.com/articles/5813 Sun, 28 Dec 2025 14:59:34 -0500 https://www.thecarlatreport.com/articles/5813-psychiatry-practice-boosters-fifth-edition-2026-4-sa-10-cme Psychiatry Practice Boosters, Fifth Edition (2026) - 4 SA / 10 CME Course

]]> http://www.thecarlatreport.com/articles/5812 Sun, 28 Dec 2025 14:50:07 -0500 https://www.thecarlatreport.com/articles/5812-psychiatry-practice-boosters-fifth-edition-2026-4-sa-10-cme Here are the 10 most visited clinical topics across all Carlat Report newsletters in 2025 with links to relevant articles.]]> http://www.thecarlatreport.com/blogs/1/post/5801 Thu, 18 Dec 2025 00:00:00 -0500 https://www.thecarlatreport.com/blogs/1-the-carlat-psychiatry-blog/post/5801-top-10-clinical-topics-of-2025-all-newsletters Topics_Most_Read.png Here are the articles your colleagues read the most in 2025 in The Carat Geriatric Psychiatry Report.]]> http://www.thecarlatreport.com/blogs/1/post/5800 Thu, 18 Dec 2025 00:00:00 -0500 https://www.thecarlatreport.com/blogs/1-the-carlat-psychiatry-blog/post/5800-top-10-carlat-psychiatry-articles-of-2025-the-carlat-geriatric-psychiatry-report CGPR_Most_Read.png This page has links and instructions for downloading your PDF and eBook copies of Psychiatry Practice Boosters, Fifth Edition (2026) and completing the 10 CME Post-Test.

]]> http://www.thecarlatreport.com/articles/5576 Mon, 03 Nov 2025 11:36:45 -0500 https://www.thecarlatreport.com/articles/5576-psychiatry-practice-boosters-fifth-edition-2026 PB5e_eBook_Cover.png This page has links and instructions for downloading your PDF and eBook copies of Psychiatry Practice Boosters, Fifth Edition (2026) and completing the 10 CME Post-Test.

]]> http://www.thecarlatreport.com/articles/5575 Fri, 24 Oct 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5575-psychiatry-practice-boosters-fifth-edition-2026 PB5e_Cover_sm.png After reading these articles, you should be able to…

]]> http://www.thecarlatreport.com/articles/5878 Wed, 01 Oct 2025 01:00:00 -0400 https://www.thecarlatreport.com/articles/5878-learning-objectives-deprescribing-psychiatric-medications-in-older-adults-cgpr-january-february-march-2026 After reading these articles, you should be able to…

]]> http://www.thecarlatreport.com/articles/5792 Wed, 01 Oct 2025 01:00:00 -0400 https://www.thecarlatreport.com/articles/5792-copy-of-learning-objectives-suicide-risk-in-older-adults-cgpr-july-august-september-2025 From anti-amyloid antibodies to digital therapeutics, geriatric psychiatry is entering a new era. We review the latest treatments for dementia and depression, including biomarkers, esketamine, and brain-stimulation tools for older adults.

]]> http://www.thecarlatreport.com/articles/5791 Wed, 01 Oct 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5791-newer-treatments-in-geriatric-psychiatry CGPR_OctNovDec_2025_Issue_Image.png Dr. Espí Forcén discusses how psychedelics, new TMS protocols, and ketamine can help older adults with depression. Learn what’s realistic, what’s safe, and how accelerated neuromodulation is changing late-life mental health care.

]]> http://www.thecarlatreport.com/articles/5790 Wed, 01 Oct 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5790-innovative-psychiatric-treatments-in-older-adults CGPR_QA1_Fernando Espi Forcen_photo_sm.png How do we balance autonomy and safety in older adults? We examine the fine line between necessary intervention and coercion and how shared decision making helps preserve dignity and trust in care.

]]> http://www.thecarlatreport.com/articles/5789 Wed, 01 Oct 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5789-when-does-involuntary-treatment-become-coercive Can better metabolism improve brain health? Dr. Palmer explains how diet, insulin resistance, and mitochondrial function affect mental illness and why the ketogenic and MIND diets may support cognitive resilience in aging.

]]> http://www.thecarlatreport.com/articles/5788 Wed, 01 Oct 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5788-metabolic-approaches-to-mental-health-and-cognitive-decline CGPR_QA2_Christopher Palmer_photo_sm.png This article reviews safe psychotropic use in older patients with heart, lung, kidney, or liver disease, helping you avoid dangerous interactions and dosing pitfalls.

]]> http://www.thecarlatreport.com/articles/5787 Wed, 01 Oct 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5787-psychiatric-medication-considerations-in-severe-medical-diseases When dementia patients suddenly worsen, is it delirium or disease progression? Learn the key behavioral and motor clues that can help you spot delirium superimposed on dementia earlier.

]]> http://www.thecarlatreport.com/articles/5786 Wed, 01 Oct 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5786-diagnosing-delirium-in-dementia A new plasma test, eMTBR-tau243, could revolutionize Alzheimer’s diagnosis by detecting tau tangles with precision and offering a faster, less invasive window into disease progression.

]]> http://www.thecarlatreport.com/articles/5785 Wed, 01 Oct 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5785-a-new-biomarker-for-tau-tangle-pathology-in-alzheimers-disease Palliative psychiatry is an emerging and thought-provoking approach that challenges us to rethink how we care for individuals with severe and persistent mental illness.

]]> http://www.thecarlatreport.com/articles/5567 Wed, 01 Oct 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5567-palliative-psychiatry Large-scale real-world data analysis reveals no single antidepressant consistently outperforms others across all outcomes. However, fluvoxamine and venlafaxine showed higher rates of discontinuation, augmentation needs, and psychiatric hospitalization in older adults.

]]> http://www.thecarlatreport.com/articles/5500 Tue, 19 Aug 2025 21:08:23 -0400 https://www.thecarlatreport.com/articles/5500-choosing-the-right-antidepressant-for-older-adults-what-works-best-in-the-real-world Research findings favor augmentation over switching strategies in treatment-resistant depression. Aripiprazole augmentation showed superior efficacy and lower fall rates compared to other approaches in older adults.

]]> http://www.thecarlatreport.com/articles/5501 Tue, 19 Aug 2025 21:07:57 -0400 https://www.thecarlatreport.com/articles/5501-augment-or-switch-it-up-antidepressant-treatment-in-older-adults Older adults undergo substantial changes in drug metabolism and elimination.]]> http://www.thecarlatreport.com/articles/6022 Sat, 02 Aug 2025 01:05:10 -0400 https://www.thecarlatreport.com/articles/6022-dementia-general-prescribing-tips