Addiction Treatment https://www.thecarlatreport.com/rss en-us CME Post-Test, Outpatient Treatment of Substance Use Disorder, CATR, January/February/March 2026 By successfully completing the test you will be awarded a certificate for 2 CME credits.

]]> http://www.thecarlatreport.com/articles/5846 Thu, 01 Jan 2026 23:00:00 -0500 https://www.thecarlatreport.com/articles/5846-cme-post-test-outpatient-treatment-of-substance-use-disorder-catr-january-february-march-2026 Learning Objectives, Outpatient Treatment of Substance Use Disorder, CATR, January/February/March 2026 After reading these articles, you should be able to…

]]> http://www.thecarlatreport.com/articles/5852 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5852-learning-objectives-outpatient-treatment-of-substance-use-disorder-catr-january-february-march-2026 Lessons From Street Psychiatry Street psychiatry brings mental health and addiction care directly to unhoused individuals through proactive outreach and long-term trust-building. Dr. Lo describes the importance of collaborating with other providers, applying harm reduction principles, engagement strategies, and how reversing traditional power dynamics helps reach vulnerable “non-utilizers” who rarely access clinics or hospitals.

]]> http://www.thecarlatreport.com/articles/5851 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5851-lessons-from-street-psychiatry CATR_QA1_Emma Lo_photo_sm.png Understanding 12-Step Programs: A Guide for Clinicians Twelve-step programs remain widely used yet poorly understood in clinical practice. This article outlines the twelve steps, demystifies what happens in meetings, how sponsorship and “90 in 90” support recovery, and how clinicians can address common reservations to make referrals more effective and patient-centered.

]]> http://www.thecarlatreport.com/articles/5850 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5850-understanding-12-step-programs-a-guide-for-clinicians Dextromethorphan Misuse Dextromethorphan misuse is common, especially among young people, yet can easily be overlooked by family and healthcare providers alike. This article reviews recognition of toxicity across the four “plateaus,” psychiatric and medical complications, and supportive management strategies—including when to consider benzodiazepines, antipsychotics, or naloxone.

]]> http://www.thecarlatreport.com/articles/5848 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5848-dextromethorphan-misuse E-Cigarettes for Smoking Cessation: Efficacy and Safety Compared with counseling alone, e-cigarettes significantly improved six-month smoking abstinence, though many participants continued vaping and did not achieve full nicotine cessation. This study supports e-cigarettes as a valuable tool for smokers who struggle with standard cessation medications.

]]> http://www.thecarlatreport.com/articles/5847 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5847-e-cigarettes-for-smoking-cessation-efficacy-and-safety Does Take-Home Naloxone Lead to Riskier Drug Use? A large prospective cohort study finds no evidence that take-home naloxone increases risky drug use behaviors. Injection frequency, opioid use, benzodiazepine use, and using alone remained unchanged—reinforcing naloxone’s role as a lifesaving harm-reduction tool without unintended risk compensation.

]]> http://www.thecarlatreport.com/articles/5845 Thu, 01 Jan 2026 00:00:00 -0500 https://www.thecarlatreport.com/articles/5845-does-take-home-naloxone-lead-to-riskier-drug-use Psychiatry Practice Boosters, Fifth Edition (2026) - 4 SA / 10 CME Psychiatry Practice Boosters, Fifth Edition (2026) - 4 SA / 10 CME Course

]]> http://www.thecarlatreport.com/articles/5813 Sun, 28 Dec 2025 14:59:34 -0500 https://www.thecarlatreport.com/articles/5813-psychiatry-practice-boosters-fifth-edition-2026-4-sa-10-cme Psychiatry Practice Boosters, Fifth Edition (2026) - 4 SA / 10 CME Psychiatry Practice Boosters, Fifth Edition (2026) - 4 SA / 10 CME Course

]]> http://www.thecarlatreport.com/articles/5812 Sun, 28 Dec 2025 14:50:07 -0500 https://www.thecarlatreport.com/articles/5812-psychiatry-practice-boosters-fifth-edition-2026-4-sa-10-cme Top 10 Clinical Topics of 2025 (All Newsletters) Here are the 10 most visited clinical topics across all Carlat Report newsletters in 2025 with links to relevant articles.]]> http://www.thecarlatreport.com/blogs/1/post/5801 Thu, 18 Dec 2025 00:00:00 -0500 https://www.thecarlatreport.com/blogs/1-the-carlat-psychiatry-blog/post/5801-top-10-clinical-topics-of-2025-all-newsletters Topics_Most_Read.png Phenobarbital for Inpatient Treatment of Alcohol Withdrawal Dr. Nisavic explains how phenobarbital offers advantages over benzodiazepines for alcohol withdrawal management, particularly in patients with benzodiazepine resistance. He details weight-based loading protocols, monitoring strategies, and the dual GABA/glutamate mechanism that may make phenobarbital superior for severe withdrawal cases.


]]> http://www.thecarlatreport.com/articles/5648 Mon, 17 Nov 2025 17:47:24 -0500 https://www.thecarlatreport.com/articles/5648-phenobarbital-for-inpatient-treatment-of-alcohol-withdrawal CATR QA1_Mladen Nisavic_image2_sm.png Delirium Tremens: Recognition, Risk, and Practical Management Dr. Gunderson provides expert guidance on recognizing and managing delirium tremens, challenging conventional wisdom about withdrawal timelines and offering practical approaches to risk stratification. He details his treatment approach for patients at high risk of developing withdrawal complications and discusses the differential diagnosis of delirium in hospitalized patients with alcohol use disorder.

]]> http://www.thecarlatreport.com/articles/5647 Mon, 17 Nov 2025 17:47:24 -0500 https://www.thecarlatreport.com/articles/5647-delirium-tremens-recognition-risk-and-practical-management CATR_QA2_Craig Gunderson_photo_sm.png Psychiatry Practice Boosters, Fifth Edition (2026) This page has links and instructions for downloading your PDF and eBook copies of Psychiatry Practice Boosters, Fifth Edition (2026) and completing the 10 CME Post-Test.

]]> http://www.thecarlatreport.com/articles/5576 Mon, 03 Nov 2025 11:36:45 -0500 https://www.thecarlatreport.com/articles/5576-psychiatry-practice-boosters-fifth-edition-2026 PB5e_eBook_Cover.png Rapid Induction of Buprenorphine in Acute Care Settings New rapid induction strategies are allowing clinicians to start buprenorphine in acute care settings.

]]> http://www.thecarlatreport.com/articles/5649 Sat, 01 Nov 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5649-rapid-induction-of-buprenorphine-in-acute-care-settings Bipolar Disorder and Addiction: Untangling a Complex Overlap When bipolar disorder and substance use disorders co-occur patients can be difficult to diagnose and treat, particularly because they often present with mixed states rather than classic mood episodes. This article reviews evidence-based treatment approaches for specific substance combinations, including valproate for alcohol use, citicoline for stimulant use, and considerations for managing this complex dual diagnosis.

]]> http://www.thecarlatreport.com/articles/5646 Sat, 01 Nov 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5646-bipolar-disorder-and-addiction-untangling-a-complex-overlap Methadone vs Buprenorphine: A Meta-Analysis A massive meta-analysis of over one million participants provides the most comprehensive real-world comparison to date of methadone versus buprenorphine for opioid use disorder. While both medications are effective, methadone shows superior treatment retention at 3, 6, and 12 months, though the medications are largely comparable in other outcomes.


]]> http://www.thecarlatreport.com/articles/5645 Sat, 01 Nov 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5645-methadone-vs-buprenorphine-a-meta-analysis Varenicline Shows Promise for Vaping Cessation The first randomized controlled trial testing varenicline for e-cigarette cessation shows encouraging results. With 45% of participants achieving 7-day abstinence at week eight compared to 30% on placebo, this study provides preliminary evidence that varenicline may be effective for helping patients quit vaping, expanding its utility beyond traditional tobacco cessation.

]]> http://www.thecarlatreport.com/articles/5644 Sat, 01 Nov 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5644-varenicline-shows-promise-for-vaping-cessation CME Post-Test, Substance Use Disorder on the Inpatient Unit, CATR, October/November/December 2025 By successfully completing the test you will be awarded a certificate for 2 CME credits.

]]> http://www.thecarlatreport.com/articles/5643 Sat, 01 Nov 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5643-cme-post-test-substance-use-disorder-on-the-inpatient-unit-catr-october-november-december-2025 Repurposing Semaglutide and Liraglutide for Alcohol Use Disorder Alcohol use disorder (AUD) is notoriously difficult to treat, with pharmacological options often underutilized or only modestly effective. But what if a medication already used for diabetes and obesity could help?

]]> http://www.thecarlatreport.com/articles/5581 Sat, 01 Nov 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5581-repurposing-semaglutide-and-liraglutide-for-alcohol-use-disorder Psychiatry Practice Boosters, Fifth Edition (2026) This page has links and instructions for downloading your PDF and eBook copies of Psychiatry Practice Boosters, Fifth Edition (2026) and completing the 10 CME Post-Test.

]]> http://www.thecarlatreport.com/articles/5575 Fri, 24 Oct 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5575-psychiatry-practice-boosters-fifth-edition-2026 PB5e_Cover_sm.png Psychedelics and Addiction Psychiatry p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px Helvetica; color: #000000}

Today, we'll be talking about psychedelics and addiction psychiatry, what they are, how they work, and what the research actually tells us. 

]]> http://www.thecarlatreport.com/blogs/2/post/5562 Mon, 13 Oct 2025 02:00:48 -0400 https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5562-psychedelics-and-addiction-psychiatry shutterstock_2689265667.jpg an abstract illustration of a human brain with colorful neural pathways or light trails (symbolizing psychedelic effects on the mind) The Rise of Long-Acting Buprenorphine p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px Helvetica; color: #000000}

There are two variations of long-acting injectable buprenorphine on the market. But what differentiates them, who might benefit, and how well do they work? Find out in today’s podcast.

]]> http://www.thecarlatreport.com/blogs/2/post/5544 Mon, 29 Sep 2025 02:00:48 -0400 https://www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/5544-the-rise-of-long-acting-buprenorphine shutterstock_2683817953.jpg A split-screen design: left side shows a syringe labeled "Sublocade", right side shows a syringe labeled "Brixadi" ( no medical dosing) Starting Long-Acting Buprenorphine During Medical Hospitalization Long-acting injectable formulations of buprenorphine can be a good treatment option for patients with opioid use disorder, particularly for those with poor adherence. However, starting long-acting injectable medications typically requires the patient to be on a stable dose of sublingual buprenorphine. Here, researchers demonstrate the feasibility of starting buprenorphine with a microinduction approach followed shortly by administration of a long-acting injection.

]]> http://www.thecarlatreport.com/articles/5468 Thu, 31 Jul 2025 20:25:18 -0400 https://www.thecarlatreport.com/articles/5468-starting-long-acting-buprenorphine-during-medical-hospitalization Note From the Editor-in-Chief Drug overdose mortality has increased nearly every year since the overdose epidemic began three decades ago. However, 2024 saw an unprecedented drop in overdose deaths across the country. Researchers are working to better understand this change, but it is almost certain that increasing availability of naloxone, widespread adoption of harm reduction practices, and improving rates of MOUD treatment played important roles in this encouraging shift.

]]> http://www.thecarlatreport.com/articles/5463 Thu, 31 Jul 2025 20:24:05 -0400 https://www.thecarlatreport.com/articles/5463-note-from-the-editor-in-chief Learning Objectives, Substance Use Disorder on the Inpatient Unit, CATR, October/November/December 2025 After reading these articles, you should be able to…

]]> http://www.thecarlatreport.com/articles/5650 Tue, 01 Jul 2025 01:00:00 -0400 https://www.thecarlatreport.com/articles/5650-learning-objectives-substance-use-disorder-on-the-inpatient-unit-catr-october-november-december-2025 CME Post-Test, Psychotherapy For Addiction, CATR, July/August/September 2025 By successfully completing the test you will be awarded a certificate for 2 CME credits.

]]> http://www.thecarlatreport.com/articles/5470 Tue, 01 Jul 2025 01:00:00 -0400 https://www.thecarlatreport.com/articles/5470-cme-post-test-psychotherapy-for-addiction-catr-july-august-september-2025 Learning Objectives, Psychotherapy For Addiction, CATR, July/August/September 2025 After reading these articles, you should be able to…

]]> http://www.thecarlatreport.com/articles/5469 Tue, 01 Jul 2025 01:00:00 -0400 https://www.thecarlatreport.com/articles/5469-learning-objectives-psychotherapy-for-addiction-catr-july-august-september-2025 Buprenorphine Induction Using Long-Acting Injection Buprenorphine induction typically requires that a patient experience moderate opioid withdrawal before starting the medication in order to avoid precipitating severe withdrawal symptoms. This waiting period is uncomfortable and can be a treatment barrier. In this study, researchers develop and test an induction protocol using injectable buprenorphine that gets around this initial waiting period.

]]> http://www.thecarlatreport.com/articles/5467 Tue, 01 Jul 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5467-buprenorphine-induction-using-long-acting-injection Supporting Sobriety With 12-Step Facilitation Dr. Nowinski explains the rationale behind the development of twelve-step facilitation (TSF) and how it blends traditional models of psychotherapy with peer support. He provides compelling evidence for its efficacy and presents data that TSF can even be superior to cognitive behavioral therapy and motivational enhancement therapy.

]]> http://www.thecarlatreport.com/articles/5465 Tue, 01 Jul 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5465-supporting-sobriety-with-12-step-facilitation JoeNowinskiPhD.png Motivational Interviewing Dr. Martino breaks down the basic principles of motivational interviewing and gives us an insight into how it helps patients across the spectrum of substance use disorders.

]]> http://www.thecarlatreport.com/articles/5464 Tue, 01 Jul 2025 00:00:00 -0400 https://www.thecarlatreport.com/articles/5464-motivational-interviewing SteveMartinoPhD.png