Research Update

Sublingual Atropine Drops and Clozapine-Induced Drooling

Topics: Atropine | Clozapine | Drooling | hypersalivation | Side Effects

REVIEW OF: Mubaslat O and Lambert T, Psychopharmacology (Berl) 2020;237(10):2905–2915 STUDY TYPE: Randomized placebo-controlled trial Excessive salivation or drooling is one of the more troublesome side effects of clozapine, occurring in up to 80% of patients. It is embarrassing for patients and is a factor in drug discontinuation. Aspiration pn

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