Autism

Clinical Update

Exploring the Potential Neurotoxicity of Antipsychotics in Younger Populations

Topics: Antipsychotics | Autism | Autism Spectrum Disorder | Neurotoxicity

At Carlat, we bang the drum of caution about antipsychotic use in children and adolescents. In this article, we pair rising concerns about antipsychotic neurotoxicity with the lack of efficacy evidence for off-label usage. Labeled use It is important to treat psychosis. A recent review by Goff and colleagues shows better outcomes for people who rece

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Expert Q&A

Managing Irritability in Autism

Topics: Autism | Autism Spectrum Disorder | Irritability | Symptom Assessment | Symptom Management

CCPR: Please tell us a little about the work you do. Dr. Brookman-Frazee: Most of my research is focused on children who have mental health needs, including those on the autism spectrum. I’m focused on ensuring that children, in community services and routine care, have access to evidence-based mental health practices. The “laboratory” of much of

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Research Update

Engage Those Infants: Maternal Interaction and Autism

Topics: Autism | Autism Spectrum Disorder | Connect | Connection | Dysregulation | Engagement

REVIEW OF: Schwichtenberg AJ et al, Autism 2019;23(4):821–833 Mother-infant interactions are a cornerstone of early development, supporting social and language development of children with or without autism spectrum disorder (ASD). Research on the impact of maternal behaviors on these interactions offers helpful guidance in clinical work with infants

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Research Update

Weight Gain From Aripiprazole Same as Risperidone

Topics: Antipsychotics | Aripiprazole | Autism | Autism Spectrum Disorder | Risperidone | Weight gain

Review of: Schoemakers RJ et al, J Child Adolesc Psychopharm 2019;29(3):192–196 Many providers prefer aripiprazole over risperidone for young patients due to observed lower incidence of weight gain. This is supported in studies with follow-up of less than 3 months. However, does aripiprazole fare better with long-term use? Researchers reviewed r

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Research Update

Melatonin for Insomnia in Patients With Autism

Topics: Autism | Child Psychiatry | Research Update | Sleep Disorders

Review of: Maras A et al, J Child Adolesc Psychopharmacol 2018;28(10):699–710 Treating sleep problems in youth with autism spectrum disorder (ASD) is tricky at best. One promising treatment is pediatric prolonged-release melatonin ­(PedPRM) sold under the name Slenyto. In 2017, a randomized controlled trial (funded by the manufacturer) assigned 11

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Expert Q&A

Micronutrients in Mental Health

Topics: Alternative treatments | Autism | Autism Spectrum Disorder | Complementary treatments | Dysregulation | Natural Medications | natural treatments | Nutrition

TCPR: You’ve studied micronutrients in ADHD and other psychiatric disorders. What are micronutrients?Dr. Rucklidge: They are small nutrients—vitamins, minerals, and amino acids—that are essential for your brain to function optimally. They include cofactors like B6, zinc, and magnesium that are involved in the synthesis of neurotransmitters and h

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