Depressive Disorder

Expert Q&A

Benefits of Alpha-Stim

Topics: Brain Devices | Depressive Disorder | Natural Medications | Practice Tools and Tips

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Whole-Body Hyperthermia for Depression: Effective or Too Early to Tell?

Topics: Depressive Disorder | Research Updates

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Research Update

Whole-Body Hyperthermia for Depression: Effective or Too Early to Tell?

Topics: Depressive Disorder | Research Update

Review of: Janssen CW, Lowry CA, Mehl MR, et al. Whole-body hyperthermia for the treatment of major depressive disorder: a randomized clinical trial. JAMA Psychiatry 2016;73(8):789-795:ahead of print. Study type: Randomized double-blind sham-controlled trial Saunas and hot tubs are pleasant and “therapeutic” for most of us, so it may be no sur

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Treating Complicated Grief: Grief-Focused Psychotherapy Is More Effective Than Citalopram

Topics: Depressive Disorder | DSM | Psychopharmacology Tips | Research Updates

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Research Update

Treating Complicated Grief: Grief-Focused Psychotherapy Is More Effective Than Citalopram

Topics: Depressive Disorder | DSM | Psychopharmacology Tips | Research Update

Review of: Shear M et al, JAMA Psychiatry, 2016;73:685–694; Study type: Randomized placebo-controlled trial Complicated grief (CG) is a relatively common response in those who have suffered the loss of a loved one. In DSM-5, it is listed in the section on conditions for further study, and it is called “persistent complex bereavement disorder.”

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Buprenorphine for Suicidality? Maybe

Topics: Addiction | Depressive Disorder

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Research Update

Buprenorphine for Suicidality? Maybe

Topics: Addiction | Depressive Disorder | Research Update

Subject: (Yovell Y et al, Am J Psychiatry 2016;173:491–498) Short Description: When patients become severely suicidal, we have few good treatment options. These include close monitoring (often in a locked unit), intensive psychotherapy, antidepressants (which, while effective, take weeks to work), a variety of medications to treat symptoms such a

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Research Update

Psychedelic Mushrooms May Help Treatment Resistant Depression

Topics: Depressive Disorder | Research Updates

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Does Light Therapy Work for Non-Seasonal Depression?

Topics: Depressive Disorder | Seasonal Affective Disorder

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Article

Four Newer Antidepressants: Should You Use Them?

Topics: Antidepressants | Depressive Disorder | Practice Tools and Tips | Psychopharmacology Tips | Seasonal Affective Disorder

Since 2011, 3 new antidepressants have been approved by the FDA, and another (ketamine) has been generating buzz as a potential off-label medication for depression. In this article, we’ll take a step back and review the data on vilazodone (Viibryd), levomilnacipran (Fetzima), vortioxetine (Brintellix), and ketamine. Vilazodone (Viibryd) Vilazodone

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Research Update

Getting Bullied as a Kid: Not Good for Your Mental Health

Topics: Child Psychiatry | Cognitive Behavioral Therapy | Depressive Disorder | PTSD

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Expert Q&A

Thinking Creatively About Treatment-Resistant Depression

Topics: Antidepressants | Depressive Disorder | Practice Tools and Tips | Psychopharmacology Tips | Seasonal Affective Disorder

TCPR: The term “treatment-resistant depression” is sort of thrown around a bit. I’m sure that there are various formal or informal definitions of it, but how do you think about it? Dr. Bodkin: The formal definition basically requires 2 failures of distinctly different antidepressants at robust doses for adequate duration. But personally, I thin

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Research Update

Does Light Therapy Work for Non-Seasonal Depression?

Topics: Depressive Disorder | Research Update | Seasonal Affective Disorder

(Lam R et al, JAMA Psychiatry 2016;73(1):56-63) Many studies have shown that light therapy works for seasonal affective disorder, but does it work for non-seasonal major depression? That’s less clear. Systematic reviews have yielded inconclusive results, in part because prior studies have had methodological weaknesses. A new study with a robust des

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Article

Diagnosing Depression in Children and Adolescents

Topics: Child Psychiatry | Depressive Disorder | Free Articles

Today, the idea that adolescents and children, even young children, can have a major depressive disorder is widely accepted, but that was not always the case. Debates about the age at which “true” depression could manifest itself were widespread in child and adolescent psychiatry through the late 70s and into the early 80s (Pataki CS and Carlson GA,

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Article

Antidepressants and Suicidal Ideation in Young People: A Practical Approach

Topics: Antidepressants | Child Psychiatry | Depressive Disorder

Many of you will remember that in October of 2004, the FDA announced to drug companies that they should add black-box warnings about the risk of suicidal behavior in children and adolescents started on antidepressants. This was based on an analysis of placebo-controlled, randomized trials (a total of 24 trials involving over 4,400 patients) showing that

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Expert Q&A

Antidepressant Use in Children and Teenagers

Topics: Antidepressants | Child Psychiatry | Depressive Disorder | Free Articles | Practice Tools and Tips | Psychopharmacology Tips

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Research Update

Should We Add Stimulants to SSRIs to Treat Geriatric Depression?

Topics: Depressive Disorder | Psychopharmacology Tips | Research Updates

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News of Note

Rexulti for Schizophrenia and MDD: Is It Abilify, Round 2?

Topics: Antidepressants | Depressive Disorder | News of Note

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Article

Neurostimulation Devices for Depression: An Overview

Topics: Brain Devices | Depressive Disorder | Practice Tools and Tips

When we last reviewed neurostimulation devices 3 years ago, we concluded that there was some promise—but more sizzle than beef. Now there are more devices and more data. But is there more beef? Maybe. We generally think of neurostimulation as a new technology, but its history is long. Beginning in the 1870s and through the turn of the last century,

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Article

Fisher Wallace and Alpha-Stim for Depression? Claims vs Evidence

Topics: Brain Devices | Depressive Disorder | Free Articles | Practice Tools and Tips

Carly Simon swears by it. The daytime show “The Doctors” gave it a glowing review. Ads for it seem to be invading psychiatrists’ Google search results. We’re talking, of course, about the Fisher Wallace Stimulator, touted by the manufacturer as being an effective treatment for depression, anxiety, insomnia, and pain (Fisher Wallace website). The

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