Depressive Disorder

Research Update

Study Looks at Use of TMS to Treat Depression

Topics: Depressive Disorder | Research Updates

Subject: Depression Short Description: Study Looks at Use of TMS to Treat Depression Background: Transcranial magnetic stimulation, or TMS, was approved by the FDA for treatment of major depression in October 2008. A newly published observational study evaluating the effectiveness of TMS treatment in more than 300 patients at 42 clinical sett

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Research Update

Low Dose Abilify Ineffective as Adjunct for MDD

Topics: Depressive Disorder | Research Updates

Subject: Depression Short Description: Low Dose Abilify Ineffective as Adjunct for MDD Background: Augmentation of antidepressants with antipsychotics has become a common practice, and aripiprazole (Abilify) has been FDA-approved at doses from 2 mg/day to 15 mg/day for this purpose. In a recent report, 225 patients with major depressive disor

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Research Update

Patient Preference Not a Good Predictor of Treatment Response

Topics: Depressive Disorder | Research Updates

Subject: Patient Preference Short Description: Patient Preference Not a Good Predictor of Treatment Response Background: Do patients with major depressive disorder (MDD) respond better when psychiatrists offer the type of treatment—medication or psychotherapy—that the patient prefers? And do patients’ beliefs about what causes their d

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Research Update

Depression

Topics: Depressive Disorder | Research Updates

Subject: DEPRESSION Short Description: Deep Brain Stimulation: A New Somatic Therapy for Depression? Background: Deep brain stimulation (DBS) has suddenly begun popping up in both the medical journals and the mainstream media as a potential treatment for treatment resistant depression. DBS involves the placement of tiny electrodes in the brai

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Cognitive Behavioral Therapy Versus Medications for Depression: How Do They Compare?

Topics: Depressive Disorder | Psychotherapy

Medications are more effective than therapy.” “Therapy is just as effective, but lasts longer.” Depending on your biases, you can probably find evidence to support either of the above propositions. Dozens of trials compare cognitive behavior therapy (CBT) to a waiting-list control group, and hundreds of trials examine how antidepressants co

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Cognitive Behavioral Therapy Versus Medications for Depression: How Do They Compare? [Free Article]

Topics: Depressive Disorder | Psychotherapy

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Article

Deplin: Is it Just Folate by Another Name?

Topics: Depressive Disorder | Natural Medications

Patients are probably asking you about Deplin, or L-methylfolate, a version of folic acid that is being marketed by Pamlab as an adjunctive treatment for depression. In a prior issue of TCPR (June 2009) we reviewed available information on Deplin, concluding that there’s little evidence it is any more helpful for depression than much cheaper folic aci

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Research Update

Genes Plus Environment in Psychiatry: View Positive Studies Skeptically

Topics: Depressive Disorder | Genetics and Psychiatry

Subject: GENETICS Short Description: Genes Plus Environment in Psychiatry: View Positive Studies Skeptically Background: Common sense dictates that genetic predispositions probably interact with life stressors to influence our mental health. Plenty of research has been published to evaluate whether this is actually true, but findings have bee

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Research Update

St. John’s Wort or Celexa for Minor Depression?

Topics: Antidepressants | Depressive Disorder | Natural Medications

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Research Update

Serotonin Transporter Genotype: Involved In Depression After All?

Topics: Depressive Disorder

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Research Update

Combined Antidepressants No More Effective than Monotherapy

Topics: Antidepressants | Depressive Disorder

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Research Update

“Soft” Bipolar Does Not Affect Antidepressant Treatment Outcomes

Topics: Bipolar Disorder | Depressive Disorder

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Research Update

Long-Term Exercise May Extend Remission in Depression

Topics: Antidepressants | Depressive Disorder

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Research Update

Antidepressants Found Ineffective for Subthreshold Depression

Topics: Depressive Disorder

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Article

Insomnia and Mood Disorders in Adolescents

Topics: Child Psychiatry | Depressive Disorder

Insomnia and sleep disturbance are common symptoms of depression in adults, but this is not always the case in adolescents. In fact, a group of researchers at the University of Pittsburgh who studied insomnia in depressed teens found that, compared to adults, insomnia in adolescents is different—very different. A 2005 study examined sleep differenc

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Research Update

Girls More Likely to Have Recurrent Depression

Topics: Child Psychiatry | Depressive Disorder | Women's Issues in Psychiatry

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Research Update

Vascular Depression? Not so Fast.

Topics: Depressive Disorder

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Research Update

Adjunctive Nuvigil Possibly Effective for Bipolar Depression

Topics: Bipolar Disorder | Depressive Disorder

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Research Update

Acne Increases Suicide Risk, With or Without Accutane

Topics: Depressive Disorder

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Article

Current APA/ACOG Recommendations for Managing Depression during Pregnancy in Three Scenarios

Topics: Antidepressants | Depressive Disorder | Women's Issues in Psychiatry

Considering pregnancy, taking ADs If moderate to severe depressive symptoms, delay conceiving, continue and optimize meds until stable If in early remission (started AD less than 6 months ago), delay conceiving, continue meds until stable If in full remission, but history of both recurrence and non-response to psychotherapy, continue meds

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