Depressive Disorder

Article

Current APA/ACOG Recommendations for Managing Depression during Pregnancy in Three Scenarios

Topics: Antidepressants | Depressive Disorder | Women's Issues in Psychiatry

Considering pregnancy, taking ADs If moderate to severe depressive symptoms, delay conceiving, continue and optimize meds until stable If in early remission (started AD less than 6 months ago), delay conceiving, continue meds until stable If in full remission, but history of both recurrence and non-response to psychotherapy, continue meds

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Research Update

Antidepressant Response Not Linked to Serotonin Transporter Gene

Topics: Antidepressants | Depressive Disorder | Research Updates

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Research Update

Zoloft Ineffective for Depression in Heart Failure

Topics: Antidepressants | Depressive Disorder

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Research Update

SAMe May be Effective Augmentation for Antidepressants

Topics: Antidepressants | Depressive Disorder | Natural Medications

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Article

Treating Depressed Adolescents Who Have Attempted Suicide: Results of the TASA Trial

Topics: Antidepressants | Child Psychiatry | Depressive Disorder

Historically, research into the effectiveness of antidepressants for depressed youths has been unimpressive. In the 1980s, Joaquim Puig-Antich studied the then-popular tricyclic antidepressants and found no evidence to support their effectiveness (Puig-Antich J, Arch Gen Psych 1987;44(1):81–89). To make matters worse for tricyclics, in the 1990s sever

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Article

How Do Psychotherapy and Medication Change the Brain?

Topics: Depressive Disorder | Diagnostic Testing | Free Articles | OCD | Psychotherapy

We know that for many conditions, both medications and psychotherapy work about equally well. Common sense would dictate that there is some final common pathway of neuropsychiatric change underlying the symptomatic improvements we see. But identifying what is happening in a living human brain is extremely tricky. Recently, a number of articles have revi

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Article

Editor’s Perspective: Do Antidepressants Work in Kids?

Topics: Antidepressants | Child Psychiatry | Depressive Disorder

The extent to which antidepressants are effective for pediatric depression continues to stir controversy, as discussed in this issue of CCPR. Parents, the media, and even our young patients themselves sometimes tell us that our medications don’t work and may well be dangerous. And yet, as clinicians, we know of many children who have apparently benefi

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Research Update

Depression and Suicide Attempts Over Time

Topics: Depressive Disorder

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Expert QA

Assessing Depression in Adolescents

Topics: Child Psychiatry | Depressive Disorder

What To Ask? Some key questions to help you ascertain depression in your adolescent patients Have you been feeling irritable or angry? Have you been getting in more fights than usual with your parents or siblings? Do you have such a hard time waking up in the morning that you’re often late for school? How are you doing with you schoolw

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Research Update

Fluoxetine May Prevent Relapse After Bipolar II Depressive Episode

Topics: Bipolar Disorder | Depressive Disorder

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Article

Alternative Treatments for Depression

Topics: Antidepressants | Depressive Disorder | Natural Medications | Seasonal Affective Disorder

No clinician wants to be a “pill-pusher,” and most of our patients do not want that kind of treatment. So what can we offer our depressed patients beyond medications? In this article, we’ll review the literature on nonpharmacological strategies, including dietary supplements, food recommendations, light therapy, yoga and mindfulness meditation, an

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Article

Psychotherapy for Depression: What’s Best?

Topics: Depressive Disorder | Psychotherapy

Are all psychotherapies equally effective for the treament of depression? Or do cognitive behavioral techniques clearly rise above the pack, as implied by the amount of media coverage they receive? In this article, we'll take a hard-nosed look at the evidence. Cognitive therapy (CT). Teaching patients to examine the evidence for their underlying nega

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Expert QA

Behavioral Activation for Depression

Topics: Depressive Disorder | Psychotherapy

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Expert QA

Inflammation and Depression

Topics: Depressive Disorder

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Research Update

Scopolamine as an Antidepressant?

Topics: Antidepressants | Depressive Disorder

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Research Update

Does Adding Psychotherapy Help Patients With Resistant Depression?

Topics: Depressive Disorder | Psychotherapy

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Article

Evaluating and Treating Tremor

Topics: Anxiety Disorder | Depressive Disorder

While tremor is traditionally thought of as a neurological issue, the symptom pops up often in psychiatric practice, and some basic knowledge of its diagnosis and treatment comes in handy. Case vignette: A 67-year-old woman whom I’ll call “Paula” came to see me for depression and anxiety. She ascribed her depression to her belief that neighbors

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Research Update

Role of Depression “Risk Gene” Questioned

Topics: Depressive Disorder

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Article

Transcranial Magnetic Stimulation is Approved. Now What?

Topics: Brain Devices | Depressive Disorder

One year ago we reviewed the status of transcranial magnetic stimulation for depression, and concluded with the following TCPR Verdict: “TMS for depression: Approval is highly unlikely.” We were wrong. On October 10, 2008, the FDA approved the Neuronetics Neurostar TMS machine for the treatment of patients with major depression who have failed on

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Article

The New Brain Devices in Psychiatry: A Brief Review

Topics: Brain Devices | Depressive Disorder

In this issue of TCPR, we focus on TMS (Transcranial Magnetic Stimulation), which has just been approved for treatment resistant depression. There are also other brain devices in various stages of research and development. Here is a quick run-down of four of them. VNS (Vagus Nerve Stimulation) VNS is a surgically implanted device that is FDA-approve

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