Research Update

Low Vitamin B 12 Associated with Depression in Older Adults

Topics: Depression | Folate | Supplementation | Vitamin B12

REVIEW OF: Laird E et al, Br J Nutr 2021;1–22 STUDY TYPE: Prospective cohort study Deficiencies of both vitamin B12 and folate are highly prevalent among older adults. Depending on the study, 5%–40% of adults older than 50 years have B12 deficiency. Folate deficiency ranges from 1.2% among older adults in countries that mandate folate fortific

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l-Methylfolate for Depression: Costly Mistake or Good Thinking?

Topics: Antidepressants | CAM Treatments | Deplin | Depression | Depressive Disorder | Folate | Folic Acid | l-methylfolate | methylfolate | Natural Medications | Nutrition | Pharmacology | Pharmacology Tips | Psychopharmacology | Psychopharmacology Tips | Treatment-Resistant Depression

Folate (Vitamin B9) has a long track record as a low-cost, low-risk augmentation strategy in depression. It’s also available in a more expensive form, l-methylfolate (Deplin), that promises better results but at a premium price. So, is the cost worth it? Folate pathwaysFolate (the natural form of folic acid) is a B vitamin that’s important in psych

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