Mood

Research Update

Methylphenidate Improves Mood and Boredom in Children with ADHD

Topics: ADHD | Boredom | Depression | methylphenidate | Mood

REVIEW OF: Golubchik P et al, J Child Adolesc Psychopharmacol 2021;31(4):310–314 TYPE OF STUDY: Open label, ­uncontrolled We are always looking for new angles to understand the conditions we treat. ADHD leads to significant academic and social impairments and is highly comorbid with depression and “boredom.” This study examines these associatio

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Research Update

Can We Treat Depression by Targeting Inflammation?

Topics: Antibiotic | Depression | Inflammation | Minocycline | Mood | Pharmacotherapy

REVIEW OF: Zazula R et al, Aust N Z J Psychiatry 2021;55(8):784–798 Recent data suggest inflammation may play a role in depression, prompting research into the efficacy of minocycline—a tetracycline antibiotic with anti-inflammatory effects—as an augmentation agent in the treatment of major depressive disorder (MDD). This study was a pooled

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Research Update

Psilocybin: The New Holy Grai­l for the Rapid Relief of Major ­Depression?

Topics: Depression | Ketamine | Mood | Pharmacotherapy | Psilocybin | Rapid-acting

Review of: Davis AK et al, JAMA ­Psychiatry 2020:e203285 Intravenous ketamine and intranasal esketamine (Spravato) offer hope in the search for a rapidly acting antidepressant. However, concerns regarding addiction, safety, and effect durability have prompted searches for alternative rapid-acting treatments. Psilocybin is a hallucinogen originally d

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Expert Q&A

Mental Illness and Flourishing

Topics: Depression | Mood | Personality Disorders | Psychotherapy

TCPR: You and other psychiatrists at Johns Hopkins have a way of viewing mental illness that differs from the biopsychosocial model. Tell us about that. Dr. Chisolm: We use a model called “perspectives of psychiatry” that was developed by Paul McHugh and Phillip Slavney in the 1970s. It’s really a framework that considers the origin of patients

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Clinical Update

How to Prescribe Omega-3 Fatty Acids

Topics: Antidepressant Augmentation | Complimentary Medicine | Mood | Natural Medications | natural treatments | Nutrition | Omega-3 | Research | Supplements

Omega-3 fatty acids (“fish oil”) claim broad benefits in physical and mental health and have even made it into a few treatment guidelines in psychiatry. But most products on the shelf do not have the right ingredients for psychiatric use. In this article, I’ll review how and when to use omega-3s. MechanismOmega-3s are “essential fatty acids,”

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Expert Q&A

How to Diagnose Bipolar Disorder

Topics: Bipolar Depression | Bipolar Disorder | Bipolar II | Diagnosis | DSM | Hypomania | Mania | Mixed Features | Mood

TCPR: When I ask a depressed patient if they’ve ever had manic symptoms, I often run into a problem. They say, “Of course I feel more confident, energetic, and happy ... when I’m not depressed.”Dr. Parker: As it can be hard to tease apart true hypomania from normal happiness, we’ve developed a rating scale to assist, the Sydney Bipolar Screene

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