Mortality

Research Update

SSRIs and Intracerebral Hemorrhage Risk

Topics: Bleeding | Citalopram | Depression | Escitalopram | Fluoxetine | Geriatric | Hemorrhagic | Intra-cerebral hemorrhage | Mortality | Paroxetine | Post-stroke depression | Prozac | Serotonin Specific Reuptake Inhibitors (SSRIs) | Sertraline | SSRIs | Stroke

REVIEW OF: Kubiszewski P et al, JAMA Neurol 2020;e203142. Epub ahead of print. Depression after strokes is very common, affecting about 50% of stroke patients. Many such patients are treated with SSRIs, which are generally effective but potentially dangerous because they can increase the risk of bleeding due to impaired platelet aggregation. This is

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Research Update

Can Antidepressants Prolong Survival in Cancer Patients?

Topics: Adherence | Cancer | Citalopram | Depression | Escitalopram | Fluoxetine | Mortality | Paroxetine | Prozac | Serotonin Specific Reuptake Inhibitors (SSRIs) | Sertraline | SSRIs

Review Of: Shoval G et al, Depress Anxiety 2019;36(10):921–929 Many cancer patients experience depression, especially those with poor prognoses. Compared with euthymic patients, depressed cancer patients are less adherent to their cytotoxic medications, and this poor adherence can worsen their long-term survival. Yet surprisingly, some studies have

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Expert Q&A

Reduced Life Expectancy in ADHD

Topics: ADHD | attention | Attention Deficit Hyperactivity Disorder | Life coaching | Life expectancy | Longevity | Medication | methylphenidate | Mortality | stimulant | Teen | teens

CCPR: To start, tell us about how the thinking has changed in terms of health consequences from ADHD. Dr. Barkley: In the 1970s, we saw ADHD as an educational disorder with impacts on school behavior and academic achievement. Around that same time, there was a parallel path recognizing ADHD as a social problem in family functioning and peer relationshi

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Research Update

Antipsychotic Use Associated With Increased Risk of Mortality

Topics: Antidepressant Augmentation | Antipsychotics | Aripiprazole | Mortality

REVIEW OF: Gerhard T et al, PLoS One 2020;15(9):e0239206 TYPE OF STUDY: Population-based comparator cohort study We know that atypical antipsychotics increase mortality in elderly patients with dementia—the FDA has long required a black box warning to that effect. But are these medications also dangerous when prescribed to younger people with depres

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