Parkinson’s Disease

Expert Q&A

Treating Agitation in Patients with Dementia

Topics: Agitation | Alzheimers | Antipsychotics | Benzodiazepines | BPSD (behavioral and psychological symptoms of dementia) | Dementia | Lewy Body Dementia | Parkinson’s Disease | Pharmacotherapy | Sundowning

CHPR: Can you tell us about yourself and your background? Dr. Metzger: I’m the medical director of psychiatry at Hebrew SeniorLife and an assistant professor of psychiatry at Harvard Medical School. My work also includes training residents and geriatric medicine fellows who rotate through our facility. CHPR: You participated in the psychopharmacol

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How to Use Pramipexole

Topics: Depression | Parkinson’s Disease | Pramipexole

Pramipexole is a selective agonist at the dopamine D3 receptor, which is thought to regulate hedonic drive. It is FDA approved in Parkinson’s disease and restless legs syndrome, and has five randomized controlled trials in depression. In unipolar depression it worked as monotherapy or augmentation, and in bipolar depression it worked as augmentation o

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