Psychotic Depression

Clinical Update

Modern Challenges of Delusional Disorder

Topics: Antipsychotics | Delusional Disorder | Pimozide | Psychosis | Psychotic Depression

While positive symptoms like hallucinations and delusions are among the more treatment-responsive symptoms of schizophrenia, the treatment of delusional disorder often proves much more vexing. Delusional disorder is often a diagnosis of exclusion requiring that you rule out other causes like schizophrenia, primary mood disorder, or substance-induced ps

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Research Update

An Answer for Psychotic Depression

Topics: Antidepressants | Antipsychotics | Deprescribing | Depression | Depressive Disorder | olanzapine | Pharmacology | Pharmacology Tips | Psychosis | Psychotic Depression | Research | Research Update | Tardive dyskinesia

REVIEW OF: Flint AJ et al, JAMA 2019;322(7):622–631 TYPE OF STUDY: Randomized, placebo-controlled trial Psychotic features in depression indicate a more severe form of the disease, with a higher risk of hospitalization and double the rate of disability compared with non-psychotic depression. A combination of an antipsychotic and an antidepressant is

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