Clinical Update

How to Use SAMe in Clinical Practice

Topics: Alternative treatments | Antidepressant Augmentation | Complimentary Medicine | Natural Medications | natural treatments | Novel drug | SAMe

S-adenosylmethionine (SAMe) is an over-the-counter supplement that’s usually lumped with the complementary and alternative (CAM) therapies in psychiatry. However, it is one of a few CAM therapies with efficacy that rivals standard medications. SAMe raises levels of serotonin, dopamine, and norepinephrine, acting in some ways like the fabled triple reu

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