Weight Loss Medications

In Brief

Lybalvi: The Diet Olanzapine

Topics: Antipsychotics | Metabolic syndrome | Metformin | News of Note | Novel drug | Obesity | olanzapine | Side Effects | Waist circumference | Weight gain | Weight Loss Medications

Lybalvi is a new combo pill that aims to overcome the dreaded metabolic effects of olanzapine by pairing it with the opioid antagonist samidorphan. Patients still gain weight on Lybalvi, though not as much as they do on olanzapine. In the three controlled trials that compared the two drugs, the weight gain on Lybalvi was 5 lb less at six months, 3 lb le

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Brief Clinical Update

Metformin ER Recalled Due to Cancer Risk

Topics: Antipsychotics | Generics | Metformin | Weight gain | Weight Loss Medications

Metformin is often prescribed to our patients to prevent weight gain on antipsychotics, but recently the FDA discovered that large batches of various metformin ER formulations may be contaminated with a carcinogen. Voluntary recalls of metformin ER began in May 2020 and have continued to the present. The result is drug shortages, fear, and an unanswered

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Expert Q&A

Medication Side Effects Part II: Weight Gain, Akathisia, Hair Loss, and Orthostasis

Topics: Akathisia | Falls | Hair loss | Orthostasis | Pharmacology Tips | Psychopharmacology Tips | Side Effects | Weight Loss Medications

Editor’s note: In the June/July issue, Dr. Mago shared a sampling of his strategies for nausea, sweating, and dry mouth. We wrap up that conversation here with a few more tips on managing side effects. Weight gain TCPR: What’s your approach to antipsychotic-induced weight gain? Dr. Mago: Prevention is better than treatment. So, when possible, we

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News of Note

FDA Approves New Weight Drug

Topics: News of Note | Weight Loss Medications

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