LAIs are sometimes used for children and adolescents who need antipsychotics for severe illness but have difficulty consistently taking oral meds.  

Growing body of research supports both efficacy and safety in kids.

Lower risk for EPS and a broad spectrum of efficacy make this an appealing first-choice agent.

Lower risk for EPS and a broad spectrum of efficacy make this an appealing first-choice agent.

Well-tolerated and inexpensive alternative to second-generation antipsychotics, especially when trying to avoid EPS and metabolic side effects; however, efficacy data in kids are more limited compared to newer agents.

The only drug with convincing evidence based on years of clinical experience to help treatment-resistant schizophrenia, but only minimal data in children. Consider in severe cases, after failure of other agents.

The only drug with convincing evidence based on years of clinical experience to help treatment-resistant schizophrenia, but only minimal data in children. Consider in severe cases, after failure of other agents.

This drug offers some advantages, including no need for titration, once-daily dosing, relatively low-moderate metabolic profile, and relatively low QT prolongation risk. 

Haloperidol is an effective, inexpensive first-generation antipsychotic with a long history of experience and use even in kids, but clinical utility is limited due to potential for EPS, prolactin elevation, and TD.

The only drug with convincing evidence based on years of clinical experience to help treatment-resistant schizophrenia, but only minimal data in children. Consider in severe cases, after failure of other agents.