The Carlat Psychiatry Report

The Antipsychotic-Stimulant Combo

As antipsychotic indications have spread, more patients are taking them in combination with their opposite: a stimulant. We look at the risks, search for scenarios where it might make sense, and come up with an action plan for this paradoxical pairing.

Patients with genetic risks for schizophrenia and bipolar disorder often present with prodromal symptoms of the illness, but the most effective treatment may surprise some. It’s not a medication.

Mitochondria regulate the body’s energy stores, and they are thought to play a causal role in bipolar disorder. This analysis gathered at seven therapies that improve mitochondrial function and looked at how they work in bipolar disorder.

Both these medications work in bipolar depression, but this analysis compared them head-to-head for a different primary outcome: Cognition in bipolar disorder.

Psychiatry Practice Boosters, Fourth Edition (2023)
Teaches you the key points of 63 of the most clinically relevant studies in psychiatry.
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General Psychiatry
Using SAMe In Clinical Practice with Garrett Rossi, MD
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General Psychiatry
Throwback Thursday: Brief Therapy for ADHD
You started a stimulant medication for a young woman with ADHD. When she returns her symptoms are 70% better, but what can we do about the rest? Today a conversation with...
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