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Research Update

Catatonia and Delirium Can Coexist—and Lorazepam May Help

July 7, 2026

Victoria Hendrick, MD. Dr. Hendrick has no financial relationships with companies related to this material.

Although DSM-5-TR cautions against diagnosing catatonia and delirium at the same time, real-world patients do not always fit neatly into one category. A prospective quality-improvement study of more than 700 medical inpatients found substantial overlap between the two syndromes, with implications for screening and treatment.

Assessing and Treating Catatonia

March 23, 2022

Stephan Heckers, MD

Stephan Heckers, MD William P. and Henry B. Test Professor Chair, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center. Psychiatrist-in-Chief, Vanderbilt Psychiatric Hospital. Nashville, TN. Dr. Heckers has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Patients experiencing catatonia often improve quickly with benzodiazepines, but how can we help patients who fail to respond? Dr. Heckers summarizes the management of catatonia, including refractory cases, and tells us of other illnesses to consider in our differential diagnoses.

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