QTc prolongation - Page 1 | CARLAT PUBLISHING

Clinical Update

Update on Psychocardiology for Older Adults

October 1, 2026

Roy Williams, MD, MPH. Transplant psychiatry and consultation-liaison psychiatry, Baylor College of Medicine, Houston, TX.

Dr. Williams has no financial relationships with companies related to this material.

Is it the heart or the mind—and which psychotropic is safe to prescribe? This update reviews QTc risk, orthostasis, and metabolic effects across antidepressants and antipsychotics in cardiac patients.

Research Update

Escitalopram Doesn't Replace Citalopram for Agitation in Alzheimer's Disease

October 1, 2026

Carlat Staff

Compiled by Carlat Editorial Staff and Reviewed by the Editor-in-Chief and the Editorial Board.

Staff members have no financial relationships with companies related to this material.

Citalopram works for agitation in Alzheimer's disease but comes with QTc concerns and strict dosing limits. Escitalopram, its purer enantiomer, seemed like an obvious fix. Is it as effective for agitation?

What You Need to Know About Gepirone (Exxua) | Benefits, Side Effects, and Review of Trials

September 27, 2024

Chris Aiken, MD. and Greg Malzberg, MD

In this video, Dr. Chris Aiken, Editor-in-Chief of The Carlat Psychiatry Report, provides a comprehensive review of Gepirone, also known as Exxua, a newly FDA-approved antidepressant for major depressive disorder in adults. Gepirone is unique due to its classification as an azipirone, a class of medications that work as serotonin 5-HT1A receptor agonists.

QT Intervals in Psychiatric Practice

June 19, 2023

Victoria Hendrick, MD. and Prabhjot Gill

Several psychiatric medications prolong the QTc interval and place patients at risk of the dreaded torsade de pointes. Some patients are particularly vulnerable to QTc prolongation: the elderly, patients with heart disease and electrolyte imbalances, and patients taking certain medications, like thioridazine and ziprasidone. In this podcast, we provide a step-by-step guide so that you can keep your patients safe from this cardiovascular side effect.