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Home » Newsletters » The Carlat Psychiatry Report
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The Carlat Psychiatry Report

Psychiatric Medications: Effects and Side Effects (April) | 2008

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Pristiq vs. Effexor

April 1, 2008
After many years of trying, Wyeth finally received FDA approval for its new antidepressant, Pristiq (desvenlafaxine). Don’t get too excited, though – Pristiq is simply the active metabolite of Effexor and it’s unclear whether it adds anything of value to our current quiver of antidepressants. Read More

Serious But Rare Antidepressant Side Effects

April 1, 2008
We typically warn our patients about common side effects, such as headache, GI distress and sexual dysfunction when we start SSRIs. Here are some of the side effects that we don’t necessarily talk to patients about, but should be able to recognize and discuss in particular contexts. Read More

Apparent effectiveness of antidepressants is inflated by publication bias

April 1, 2008
A former FDA reviewer and his colleagues obtained all FDA data on studies of 12 antidepressants approved between 1987 and 2004. They then scoured the journals to figure which of these studies had been published. They found that of the 74 FDA-registered trials of antidepressants, 23 (31%) had never been published. Read More

Antidepressants are effective primarily for severe depression

April 1, 2008
Researchers used the Freedom of Information Act to retrieve all clinical trials data from the FDA on four different antidepressants: fluoxetine, venlafaxine, nefazodone, and paroxetine. Read More

Side Effects of Antipsychotics in the Elderly

April 1, 2008
Dr. Jeste, I know that you were responsible for some of the original research demonstrating that tardive dyskinesia is a possible side effect of antipsychotics. Why were you interested in the topic? Read More

Learning Objectives, Psychiatric Medications: Effects and Side Effects, TCPR, April 2008

April 1, 2008
After reading these articles, you should be able to… Read More
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Editor-in-Chief
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Chris Aiken, MD
Dr. Aiken is the Editor in Chief of The Carlat Psychiatry Report; director of the Mood Treatment Center in North Carolina, where he maintains a private practice combining medication and therapy along with evidence-based complementary and alternative treatments; and Assistant Professor NYU Langone Department of Psychiatry. He has worked as a research assistant at the NIMH and a sub-investigator on clinical trials, and conducts research on a shoestring budget out of his private practice. Follow him on Twitter and find him on LinkedIn.

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