Chris Aiken, MD

Narcissism

June 30, 2025

Kellie Newsome, PMHNP and Chris Aiken, MD

Two ways to approach narcissism in therapy, and how AI can ramp up the problem.

Psychopharm Secrets: Coming Off Meds

June 23, 2025

Kellie Newsome, PMHNP and Chris Aiken, MD

There’s a hidden placebo response to watch for when patients stop meds on their own.

Psychopharm Secrets: Starting Meds

June 16, 2025

Kellie Newsome, PMHNP and Chris Aiken, MD

We look at a hidden placebo effect that can confuse the picture when starting a medication.

AI in Practice

June 9, 2025

Kellie Newsome, PMHNP and Chris Aiken, MD

Artificial Intelligence is full of medical information. Here’s how to use it wisely.

CLINICAL UPDATE

Generic Lurasidone Shifts the Balance in Bipolar Depression

June 1, 2025

Chris Aiken, MD

Chris Aiken, MD. Editor-in-Chief, The Carlat Psychiatry Report. Assistant Professor, NYU Langone Department of Psychiatry. Practicing psychiatrist, Winston-Salem, NC.

Dr. Aiken has no financial relationships with companies related to this material.

Lurasidone was heralded as a game changer when it first gained FDA approval for bipolar depression in 2013. In 2023, this article covers what that means for patients with bipolar disorder and schizophrenia who can now afford its $10–$20/month cost.

Cobenfy: A New Antipsychotic

June 1, 2025

Chris Aiken, MD

Chris Aiken, MD. Editor-in-Chief, The Carlat Psychiatry Report. Assistant Professor, NYU Langone Department of Psychiatry. Practicing psychiatrist, Winston-Salem, NC.

Dr. Aiken has no financial relationships with companies related to this material.

Last fall, the FDA approved xanomeline/trospium (Cobenfy) for adults with schizophrenia. Here's a closer look at this treatment.

Should You Test MTHFR?

May 5, 2025

Kellie Newsome, PMHNP and Chris Aiken, MD

MTHFR is a genetic test that aims to clarify who will respond to methylfolate in depression. But is it worth testing for?

Psych Meds That Cause Weight Loss

May 1, 2025

Chris Aiken, MD

Chris Aiken, MD. Editor-in-Chief, The Carlat Psychiatry Report. Assistant Professor, NYU Langone Department of Psychiatry. Practicing psychiatrist, Winston-Salem, NC.

Dr. Aiken has no financial relationships with companies related to this material.

Some patients will only take a psych med that is weight neutral. We found nine that can cause weight loss.

Folate and Depression

April 28, 2025

Kellie Newsome, PMHNP and Chris Aiken, MD

We learn how psychiatrists figured out that low folate causes depression, and how the vitamin can treat depression even when serum levels are normal.

Folate, Valproate, and Lamotrigine

April 21, 2025

Kellie Newsome, PMHNP and Chris Aiken, MD

We interview Victor Hoffbrand on the discovery of folate and look at how this vitamin can help or harm the action of anticonvulsants in bipolar disorder.