With Vrylar’s new approval, there are now four atypicals antipsychotics with an indication in bipolar depression. Only two of these, however, are known to work in mania as well as depression. None of the atypicals stands out as the perfect choice for bipolar depression, but there are pros and cons to each that make them fitter better with certain patients.
A teen is using substances—how do you decide what kind of treatment makes sense? Outpatient therapy? A more structured program? We’re breaking it down.