Antipsychotics offer remarkable, even lifesaving treatment for children and adolescents, however, their side effects include metabolic and neurologic problems, including neurotoxicity. This clinical update guides you through a rational process for employing these powerful medications when necessary but also reducing and discontinuing them when possible.

Probiotics may reduce metabolic side effects on antipsychotics, but do they need dietary fiber to work?

Once weight gain occurs with antipsychotic treatment in children and adolescents it is difficult to reverse. How should you select and prescribe SGAs to prevent it? Which additional medications are effective in preventing weight gain from SGAs? This clinical update gives you information to help prevent this common and problematic side effect.

This study looked at adjunctive topiramate for weight in a patient population inherently more vulnerable to cardiometabolic disturbance.