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Home » Paxil CR

Paxil CR

January 1, 2003
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information
Dr. Richard Naimark, a psychiatrist in private practice at Chestnut Hill Counseling in Dover, New Hampshire, relates a tidbit that tempers TCR’s fairly lukewarm review of Paxil CR.

“I’ve treated a woman for depression for a few years who had done quite well on Paxil but complained of dizziness as a side effect. I tried her on other SSRIs as well as Effexor and Wellbutrin, but nothing helped as much as Paxil. One day as I was listening to her, it dawned on me that her dizziness followed a predictable pattern of having its onset about 6 hours after her dose. This was consistent with a mild SSRI discontinuation syndrome. I switched her to paxil CR, and the dizziness completely disappeared, presumably because of the lack of discontinuation side effects.” We protested to Dr. Naimark that paxil CR has the same discontinuation half-life as the original. “I realize that,” he said, “but my thought is that the longer transit time in the gut smoothed out blood levels enough to effectively lengthen the half life.”
General Psychiatry
www.thecarlatreport.com
Issue Date: November 1, 2006
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Table Of Contents
Paxil CR
Dr. John O’Reardon on Treatment-Resistant Depression
Paxil CR: Paxil by any other name...
Lexapro: The Son of Celexa
Effexor XR: Is it really as good as they say it is?
St. John’s Wort: Wilting in America
The First Antidepressant
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