David Mischoulon, MD, PhD Assistant Professor of Psychiatry, Harvard Medical School Director of Alternative Remedy Studies, Depression Clinical and Research Program, Massachusetts General Hospital Dr. Mischoulon has disclosed that he has no significant relationships with or financial interests in any commercial companies pertaining to this educational activity. The author has disclosed that acupuncture has not been approved by the U.S. Food and Drug Administration for use in the treatment of depression or substance abuse. Please consult product labeling for the approved usage of this treatment.