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Research Update

Antidepressant Discontinuation Symptoms

Victoria Hendrick, MD

Victoria Hendrick, MD. Dr. Hendrick has no financial relationships with companies related to this material.

Prior estimates put antidepressant discontinuation symptom rates as high as 56%. A rigorous meta-analysis of nearly 21,000 patients arrives at a very different number—and it changes how clinicians should counsel patients before tapering.


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Clinical Update

On, Off, and On Again: The Hidden Risks of Antidepressant Discontinuation

Victoria Hendrick, MD and Michael Gitlin, MD

Victoria Hendrick, MD. Chief, Inpatient Psychiatry, Olive View-UCLA Medical Center; Editor-in-Chief, The Carlat Hospital Psychiatry Report.

Michael J. Gitlin, MD. Distinguished Professor of Clinical Psychiatry; Director, Mood Disorders Clinic, Geffen School of Medicine, Los Angeles, CA.

Dr. Hendrick and Dr. Gitlin have no financial relationships with companies related to this material.

What do you do when a patient restarts an antidepressant, only to find it doesn't work as well the second time around?


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Expert Q&A

Distinguishing Medical From Psychiatric Catatonia

Fernando Espi Forcén, MD, PhD.

Fernando Espí Forcén, MD, PhD. Psychiatrist, Short Term Unit, Belmont, MA; Assistant Professor, Harvard Medical School, Boston, MA.

Dr. Espí Forcén has no financial relationships with companies related to this material.

You’ve diagnosed catatonia, but what's driving it? Dr. Fernando Espí Forcén discusses when to suspect an underlying medical cause, why delirium and seizure history complicate the picture, and how lorazepam response and antipsychotic use differ between psychiatric and medical catatonia in hospitalized patients.


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Clinical Update

Psychogenic Polydipsia: When Water Becomes Dangerous

Brian Holoyda, MD, MPH, MBA

Brian Holoyda, MD, MPH, MBA. Chief Psychiatrist, Contra Costa County Detention Health Services, Martinez, CA.

Dr. Holoyda has no financial relationships with companies related to this material.

Could excessive water intake be driving your patient's confusion? Psychogenic polydipsia can mimic psychiatric decompensation and lead to dangerous hyponatremia. This article reviews recognition, acute management, and pharmacologic options for recurrent cases on the inpatient unit.


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