There are many longer-acting methylphenidate preparations. Two good options are Concerta and Ritalin LA, available as generics.

Vyvanse may have a gentler, “smoother” side effect profile than other amphetamines, and probably has a lower risk of diversion or misuse.

Vyvanse may have a gentler, “smoother” side effect profile than other amphetamines, and probably has a lower risk of diversion or misuse.

Vyvanse may have a gentler, “smoother” side effect profile than other amphetamines, and probably has a lower risk of diversion or misuse.

Guanfacine’s advantages over stimulants include no worsening of tic disorders, lack of misuse potential, and no insomnia.

A patch option in the amphetamine class of stimulants for kids who cannot use the wide array of oral stimulants available today.

Good drug with very long history of experience, available in short- and long-acting formulations as generics.

Focalin is just Ritalin but more potent. It’s available as a generic and may mean fewer tablets for patients. Focalin XR only recently went generic.

Clonidine is a good option in kids with ADHD who also have tics, who experience excessive anxiety or insomnia on stimulants, or in whom substance misuse is a concern.

Unlike stimulants, atomoxetine has no abuse potential, causes less insomnia and anxiety, and is unlikely to worsen tics.