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Home » Topics » Addiction Treatment

Addiction Treatment
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Fact Sheet

Disulfiram (Antabuse) for Children and Adolescents

September 22, 2023
Joshua Feder, MD, Elizabeth Tien, MD, and Talia Puzantian, PharmD, BCPP

Dr. Feder, Dr. Tien, and Dr. Puzantian have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Disulfiram is an aversive treatment, causing a buildup of ethanol’s metabolite acetaldehyde in the serum, which in turn causes symptoms such as flushing, dizziness, nausea, and vomiting.




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Fact Sheet

Buprenorphine/Naloxone (Bunavail, Suboxone, Zubsolv) for Children and Adolescents

September 22, 2023
Joshua Feder, MD, Elizabeth Tien, MD, and Talia Puzantian, PharmD, BCPP

Dr. Feder, Dr. Tien, and Dr. Puzantian have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

The combination product is preferred over buprenorphine alone for maintenance because the addition of naloxone affords it a lower potential for injection misuse. 




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Fact Sheet

Buprenorphine (Sublocade) for Children and Adolescents

September 22, 2023
Joshua Feder, MD, Elizabeth Tien, MD, and Talia Puzantian, PharmD, BCPP

Dr. Feder, Dr. Tien, and Dr. Puzantian have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Buprenorphine alone was previously preferred for initial (induction) phase of treatment, with buprenorphine/naloxone combination preferred for maintenance treatment (unsupervised administration).




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Fact Sheet

Acamprosate (Campral) for Children and Adolescents

September 22, 2023
Joshua Feder, MD, Elizabeth Tien, MD, and Talia Puzantian, PharmD, BCPP

Dr. Feder, Dr. Tien, and Dr. Puzantian have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Acamprosate and naltrexone show similar reduced rates of relapse, but acamprosate is associated with more diarrhea, while naltrexone is associated with more nausea, fatigue, and somnolence; acamprosate is preferred in patients with hepatic impairment.




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Clinical Guidance

Substance Use Medications for Children and Adolescents

September 22, 2023
Joshua Feder, MD, Elizabeth Tien, MD, and Talia Puzantian, PharmD, BCPP

Dr. Feder, Dr. Tien, and Dr. Puzantian have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

The primary treatment of substance use disorders in teens remains behavioral therapies, particularly motivational interviewing, as well as harm reduction measures.  




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CME Post-Test, Revisiting Opioid Use Disorder, CATR, Jul/Aug/Sept 2023

May 29, 2023
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Learning Objectives, Revisiting Opioid Use Disorder, CATR, Jul/Aug/Sept 2023

May 29, 2023
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

After reading these articles, you should be able to…


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Research Update

Intravenous Buprenorphine Microinduction

May 29, 2023
Noah Capurso, MD and Marissa Bayerl, APRN
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Marissa Bayerl, APRN, and Noah Capurso, MD, MHS. Ms. Bayerl and Dr. Capurso have no financial relationships with companies related to this material.

Buprenorphine microinduction can be a useful method of starting BUP induction, however it is not always feasible, particularly in the hospital setting. Here, we discuss the development of an intravenous microinduction protocol that could provide an alternative to the usual sublingual and transdermal routes of administration. 


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Clinical Update

What Psychiatrists Need to Know About Intravenous Drug Use and Endocarditis

May 29, 2023
Kenechukwu Mezue, MD, MSc and Bernardo Lombo, MD, FACC
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Kenechukwu Mezue, MD, MSc. Clinical Fellow in Cardiovascular Medicine, Yale School of Medicine, New Haven, CT.

Bernardo Lombo, MD, FACC. Assistant Professor of Cardiology, Yale School of Medicine, New Haven, CT.

Dr. Mezue and Dr. Lombo have no financial relationships with companies related to this material.

Infective endocarditis (IE) is a dangerous and potentially life-threatening complication of intravenous drug use. This article explores the pathogenesis of IE, key symptoms to recognize, and the crucial steps to take if an infection is suspected. 


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Expert Q&A

Starting Medication for Opioid Use Disorder

May 29, 2023
Gretchen Hermes, MD, PhD
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

CATR-QA2-Headshot_Hermes.jpgGretchen Hermes, MD, PhD. 

Medical Director, APT Foundation; Assistant Professor, Department of Psychiatry, Yale School of Medicine, New Haven, CT.

Dr. Hermes has no financial relationships with companies related to this material.

Dr. Hermes discusses the intricacies of medications for opioid use disorder by outlining the advantages, disadvantages, and side effect profile of each. She will help you choose the best treatment approach for your patients with opioid use disorder by providing a review of relevant literature and gives you language to use in the clinic.


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