Paul Barkopoulos, MD.

EXPERT Q&A

QT Intervals in Psychiatric Practice

October 1, 2022

Victoria Hendrick, MD and Paul Barkopoulos, MD.

Paul Barkopoulos, MD. Clinical Assistant Professor, Psychiatry & Biobehavioral Sciences, UCLA David Geffen School of Medicine and Olive View UCLA Medical Center, Los Angeles, CA.

Victoria Hendrick, MD. Editor-in-Chief, The Carlat Hospital Psychiatry Report; Chief, Inpatient Psychiatry, Olive View UCLA Medical Center.

Dr. Barkopoulos and Dr. Hendrick, authors for this educational activity, have no relevant financial relationship(s) with ineligible companies to disclose.

Several psychiatric medications prolong the QTc interval and place patients at risk of the dreaded torsade de pointes. Some patients are particularly vulnerable to QTc prolongation: the elderly, patients with heart disease and electrolyte imbalances, and patients taking certain medications, like thioridazine and ziprasidone. We provide a step-by-step guide so that you can keep your patients safe from this cardiovascular side effect.

Psilocybin: The New Holy Grail for the Rapid Relief of Major Depression?

July 14, 2021

Paul Barkopoulos, MD.

Paul Barkopoulos, MD. Dr. Barkopoulos has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Like ketamine, psilocybin works quickly to relieve depression, but it’s not habit-forming and its effects might last longer.

SSRIs and Intracerebral Hemorrhage Risk

May 21, 2021

Paul Barkopoulos, MD.

Paul Barkopoulos, MD. Dr. Barkopoulos has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

SSRIs help relieve post-stroke depression but increase the risk of intracerebral hemorrhage. This study gives us tips to reduce this risk.

Can Antidepressants Prolong Survival in Cancer Patients?

May 21, 2021

Paul Barkopoulos, MD.

Paul Barkopoulos, MD. Dr. Barkopoulos has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Antidepressant adherence is linked with increased survival among cancer patients.

Antipsychotic Dosing: How High?

April 12, 2021

Paul Barkopoulos, MD.

Paul Barkopoulos, MD. Dr. Barkopoulos has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

How high should we go when dosing antipsychotics in schizophrenia? A recent meta-analysis of 68 studies examined dose-response relationships in randomized controlled trials of antipsychotic medications for schizophrenia and schizoaffective disorder.