The Carlat Addiction Treatment Report

Medical Issues (April/May/June) | 2025

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Learning Objectives, Medical Issues in Addiction, CATR, April/May/June 2025

April 1, 2025

After reading these articles, you should be able to…

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Note from the Editor-in-Chief, CATR, April/May/June 2025

April 1, 2025
Noah Capurso, MD, MHS

Sublocade is a long-acting form of injectable buprenorphine that has shown promise for patients with opioid use disorder and adherence challenges. Here, we cover recent updates to prescribing guidelines that may expand its clinical utility.

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GLP-1 Receptor Agonists in Addiction Treatment: The Next Big Thing or Just Hype?

April 1, 2025
Michael Weaver, MD, FASAM and Noah Capurso, MD, MHS

GLP-1 agonists have taken the world by storm, especially for weight loss—but emerging evidence suggests they may also play a role in addiction treatment. In this article, we review the latest research to highlight when these medications might offer the greatest benefit for patients with substance use disorders.

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Xylazine and Peripheral Wounds

April 1, 2025
Joseph D’Orazio, MD

Xylazine is a non-opioid sedative commonly added surreptitiously to illicit opioids. One particularly challenging adverse effect of xylazine exposure is the development of peripheral wounds, some of which can be severe, necessitating surgical intervention and even amputation. In this interview, Dr. D’Orazio teaches us how these wounds might be caused, how to discuss them with your patients, and the best treatment approach.

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Substance Use and Dental Health: What Clinicians Need to Know

April 1, 2025
Aviv Ouanounou, DDS, MSc

Substance use is associated with many dental problems, some of which can even be life threatening. Here, Dr. Ouanounou discusses which specific dental issues addiction treatment providers need to be on the lookout for. He covers the basics of dental examination and teaches us when referral to specialty care is warranted.

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A Rapid Initiation Protocol for Long-Acting Injectable Naltrexone for Opioid Use Disorder

April 1, 2025
Noah Capurso, MD, MHS

Injectable naltrexone can be an effective treatment for opioid use disorder, but it requires complete abstinence before initiation—a process that can take more than a week and cause significant discomfort. Here, researchers evaluate a new protocol designed to accelerate this induction period and improve patient access.

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Cannabis Use Frequency and Cannabis Use Disorder

June 20, 2025
Aniruddha Deka, MD

Prevalence and frequency of cannabis use have increased as restrictions have been eased across the country. Here, researchers asked the question: Does frequency of cannabis use affect the likelihood of developing cannabis use disorder? The answer may surprise you.

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Understanding Viral Hepatitis in the Context of Addiction Psychiatry

April 1, 2025

Hepatitis B and C are highly prevalent in people who use drugs and can result in significant morbidity and mortality due to progressive liver disease. In this article, we cover all the basics, including screening, symptoms, and relevant laboratory testing. We give tips to provide your patients on hepatitis prevention and when to refer them to specialists for treatment. 

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CME Post-Test, Medical Issues, CATR, April/May/June 2025

April 1, 2025

By successfully completing the test you will be awarded a certificate for 2 CME credits.

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