treatment-resistant depression - Page 1

Research Update

When Antidepressants Stop Working in Older Adults

July 1, 2026

Carlat Staff

The evidence base for treatment-resistant depression was largely built on younger adults. This meta-analysis asks what works in patients 55 and older. One intervention stands out, especially when suicidality is in the picture.

Expert Q&A

Ketamine Treatment in Inpatient Psychiatry: What Clinicians Need to Know

April 1, 2026

Benjamiin D, Brody, MD

Benjamin D. Brody, MD. Associate Professor of Clinical Psychiatry; Service Chief, Acute Care Services, Department of Psychiatry, Weill Cornell Medicine, New York, NY.

Dr. Brody has no financial relationships with companies related to this material.

IV ketamine offers rapid antidepressant effects that align with the pace of inpatient care. Dr. Benjamin Brody explains how to implement subanesthetic infusions safely, monitor for dissociation and hemodynamic changes, select appropriate patients, and plan maintenance strategies once patients leave the unit.

Expert Q&A

Beyond Meds: TMS in Acute Psychiatric Care

January 1, 2026

Nicholas Trapp, MD, MS

Assistant Professor of Psychiatry; Director, Electroconvulsive Therapy Services, University of Iowa Health Care, Iowa City, IA.

Dr. Trapp has no financial relationships with companies related to this material.

Can TMS be used safely and effectively in the hospital? Dr. Nicholas Trapp shares insights on inpatient protocols, accelerated treatments like SAINT, and how to overcome logistical barriers.

Research Update

Ketamine Shows Only Modest Advantage Over Midazolam in Inpatient Depression Treatment

January 1, 2026

Victoria Hendrick, MD

Victoria Hendrick, MD. Dr. Hendrick has no financial relationships with companies related to this material.

Is ketamine really more effective than an active placebo for inpatient depression? A new randomized trial puts ketamine head-to-head with midazolam, and the results may temper early enthusiasm.

Items Tagged with 'treatment-resistant depression'

ARTICLES

When Antidepressants Stop Working in Older Adults

Ketamine Treatment in Inpatient Psychiatry: What Clinicians Need to Know

Beyond Meds: TMS in Acute Psychiatric Care

Ketamine Shows Only Modest Advantage Over Midazolam in Inpatient Depression Treatment

Medication Fact Book for Psychiatric Practice, Eighth Edition (2026)

KarXT (Cobenfy): The Breakthrough Antipsychotic That Could Change Everything

EMDR in Practice: A Clinician's Guide to Trauma Reprocessing with Roger Solomon, PhD

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Insights About a Rare Transmissible Form of Alzheimer's Disease

How to Fulfill the DEA's One Time, 8-Hour Training Requirement for Registered Practitioners

Join Our Writing Team

Insights About a Rare Transmissible Form of Alzheimer's Disease

How to Fulfill the DEA's One Time, 8-Hour Training Requirement for Registered Practitioners

Join Our Writing Team

Insights About a Rare Transmissible Form of Alzheimer's Disease

How to Fulfill the DEA's One Time, 8-Hour Training Requirement for Registered Practitioners

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