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PMS and PMDD: Mood Changes During the Menstrual Cycle

Of all the factors that contribute to mood, hormonal variations, such as those found in premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) can have a particularly strong effect. I’ve heard some people, for instance, describe PMS as a “powerful spell” that women are put under once every month. Read More

Should We Prescribe Meditation to Our Patients?

Many people claim that meditation helps them reduce stress, anxiety, or depression, but little quality evidence exists to support those anecdotes. Add to that the difficulty in designing a controlled trial of meditation—eg, how can people be blinded to their treatment group?—and it’s hard to know how to counsel patients on the effectiveness of this strategy. Read More

Schizophrenia, a condition that is thought to affect 1% of the world’s population, remains one of the most challenging psychiatric disorders to treat. Read More

New Schizophrenia Drug Fails Two Phase III Trials

Roche Pharmaceuticals’ potential new medication for schizophrenia, bitopertin (RG1678), failed its first two phase III trials. In both trials, adding bitopertin to antipsychotics for 24 weeks failed to improve persistent negative symptoms of schizophrenia as measured by PANSS (Positive and Negative Symptoms Scale) scores when compared to placebo, according to a report released by the company in January. Read More

J&J Starts Sharing Clinical Trial Information

Johnson & Johnson will begin providing all clinical trial data gathered through its Janssen pharmaceuticals arm to Yale School of Medicine’s Open Data Access (YODA) Project. Physicians and researchers will be able to request access to the anonymized data through YODA, and not the drug company. Read More

CDC: Only 1 in 6 Has Ever Talked about Alcohol with Doc

A January 2014 report from the Centers for Disease Control and Prevention says that alcohol screening and brief counseling by physicians can significantly reduce weekly alcohol consumption and binge-drinking episodes, but that only one in six people has ever talked with their doctor or other health professional about alcohol use. Read More

Medication Fact Book for Psychiatric Practice, Sixth Edition (2022)
Guidance, clinical pearls, and bottom-line assessments covering the medications you use in your...
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General Psychiatry
Using SAMe In Clinical Practice with Garrett Rossi, MD
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General Psychiatry
Psychopharm Commandment #6: MAOIs
MAOIs rank high in efficacy and are pretty well tolerated too, as long as you watch for two critical interactions.
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