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Dr. Vaughan’s Interaction

The concept of drug-drug interactions in psychiatry surfaced surprisingly recently. In 1988, a small letter was published in the American Journal of Psychiatry by Dr. D. A. Vaughan, a psychiatrist in practice in Wichita, Kansas. Dr. Vaughan described two women he had been treating for depression with tricyclics. Read More

Dr. Sandson, you've just published the definitive casebook on drug interactions (1), and you obviously have thought long and hard about the issue. What do you think psychiatrists really need to know about drug-drug interactions? Read More

What to Remember about Lithium

When it comes to Lithium, you can (thankfully) forget all about the P450 enzymes, because they don't touch this salt. Lithium enters the bloodstream, accomplishes its mysterious mood-stabilizing duties, and then is simply whisked out of the body intact by the kidneys via urine. So with Lithium, it's all about kidneys. Read More

Drug interactions are enormously complicated. In tried and true TCR fashion, I have tried to make this topic easier to stomach. Nonetheless, you can skip this article if you make a decision to avoid prescribing the following medications ... Read More

We apologize in advance. But it was inevitable that TCR would eventually have to tackle what may be the most boring topic in all of psychiatry, if not medicine in general: Drug-drug interactions. Read More

Medication Fact Book for Psychiatric Practice, Sixth Edition (2022)
Guidance, clinical pearls, and bottom-line assessments covering the medications you use in your...
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General Psychiatry
Using SAMe In Clinical Practice with Garrett Rossi, MD
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General Psychiatry
Psychopharm Commandment #6: MAOIs
MAOIs rank high in efficacy and are pretty well tolerated too, as long as you watch for two critical interactions.
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