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The Carlat Psychiatry Report

Drug-Drug Interactions in Psychiatry (July) | 2003

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Dr. Vaughan’s Interaction

July 1, 2003

The concept of drug-drug interactions in psychiatry surfaced surprisingly recently. In 1988, a small letter was published in the American Journal of Psychiatry by Dr. D. A. Vaughan, a psychiatrist in practice in Wichita, Kansas. Dr. Vaughan described two women he had been treating for depression with tricyclics. Read More

Dr. Neil Sandson on Drug Interactions

July 1, 2003

Neil B. Sandson, M.D.

Dr. Sandson, you've just published the definitive casebook on drug interactions (1), and you obviously have thought long and hard about the issue. What do you think psychiatrists really need to know about drug-drug interactions? Read More

What to Remember about Lithium

July 1, 2003

Daniel Carlat, MD

When it comes to Lithium, you can (thankfully) forget all about the P450 enzymes, because they don't touch this salt. Lithium enters the bloodstream, accomplishes its mysterious mood-stabilizing duties, and then is simply whisked out of the body intact by the kidneys via urine. So with Lithium, it's all about kidneys. Read More

Drug-Drug Interactions You Need to Know

July 1, 2003

Daniel Carlat, MD

Drug interactions are enormously complicated. In tried and true TCR fashion, I have tried to make this topic easier to stomach. Nonetheless, you can skip this article if you make a decision to avoid prescribing the following medications ... Read More

A Basic Course in Drug Metabolism

July 1, 2003

Daniel Carlat, MD

We apologize in advance. But it was inevitable that TCR would eventually have to tackle what may be the most boring topic in all of psychiatry, if not medicine in general: Drug-drug interactions. Read More

St. John’s Hot Flashes

July 1, 2003

Alan Ringold, M.D., is a psychiatrist in private practice in Palo Alto, California. He is particularly astute when it comes to drug interactions, and he clearly made the right call in the following situation. Read More