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Novel Anticonvulsants: An Update on Efficacy

In this article, we’ll review the clinical data on three of the most frequently used of the novel anticonvulsants: Trileptal (oxcarbazepine), Topamax (topiramate), and Neurontin (gabapentin). We cover Lamictal in this month’s expert interview with Nassir Ghaemi. Read More

The Kindling Hypothesis: Is It Relevant in Psychiatry?

Over the past couple of decades, psychiatry has adopted a number of anticonvulsants that effectively treat psychiatric conditions. The “kindling hypothesis” has provided a rationale for their increasing use, but what is the evidence behind this theory, and is it actually applicable for psychiatric practice? Read More

In a ruling certain to make psychiatrists and their patients happy, the DEA has finally said that doctors may give patients 90 days worth of prescriptions for schedule II controlled substances, which includes stimulants and narcotics. Read More

Placebo more effective than antipsychotics for aggression in mental retardation

In a multi-center study conducted in Great Britain and Australia, 86 adults with mental retardation (IQ < 75) and aggressive behavior were randomized to double-blind treatment with Risperdal (mean dose, 1.8 mg/day), Haldol (mean dose, 2.9 mg/day), or placebo. The primary outcome was score on the modified overt aggression scale (MOAS) at 4 weeks. Read More

The North American Prodrome Longitudinal Study is a consortium of 8 academic centers (all but one in the U.S.) seeking to develop predictors of the development of psychosis in young patients who present with prodromal symptoms. Read More

The FDA has issued a warning that Asian patients with a specific human leukocyte antigen (HLA) are at increased risk of developing life-threatening Stevens Johnson syndrome rash, and should be tested for this antigen before initiating treatment. Read More

Medication Fact Book for Psychiatric Practice, Sixth Edition (2022)
Guidance, clinical pearls, and bottom-line assessments covering the medications you use in your...
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General Psychiatry
Using SAMe In Clinical Practice with Garrett Rossi, MD
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General Psychiatry
Elvis, Adderall, and a Broken Heart - Part 1
A new medical investigation changes our understanding of Elvis Presley’s untimely death and offer some pearls for modern psychiatric practice.
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