Do antipsychotics during pregnancy increase long-term neurodevelopmental risk? Large US and Nordic registry studies, along with prospective data, provide reassuring findings. After adjusting for maternal illness, prenatal exposure was not meaningfully associated with intellectual, language, or learning disorders—important context for shared decision-making.

Does medication work for rapid reduction of anxiety? This review finds some surprising answers. 

Esketamine outperforms quetiapine in TRD remission rates, but the clinical significance of this difference remains uncertain.

How do lithium and quetiapine compare in their ability to treat acute mania in children and teens? Are they effective? Do kids go into remission? And how do their side effect profiles compare?  This clinical update can help you decide which patients might be good candidates for which medication. 

A new analysis looks at the optimal dosing for quetiapine in schizophrenia, and when to use instant vs extended release.

Both these medications work in bipolar depression, but this analysis compared them head-to-head for a different primary outcome: Cognition in bipolar disorder.