Can brain stimulation help preserve function in Alzheimer’s disease? A year-long randomized trial suggests that PC- rTMS modestly slows cognitive and functional decline, offering a potential nonpharmacologic adjunct as clinicians seek alternatives to long-term medication burden.

Not all late-life low mood requires medication. This article explores how apathy differs from depression and how behavioral activation, microgoals, and lifestyle interventions can restore motivation, improve cognition, and reduce unnecessary antidepressant exposure in older adults.

Lithium remains a powerful mood stabilizer in late life, but aging kidneys change the equation. Dr. Michael Gitlin reviews kidney-conscious dosing, monitoring by eGFR, and shared decision-making strategies to balance lithium’s benefits against renal risk in older adults.

Jaime A.B. Wilson, PhD, ABN, ABPP, MSCP. Dr. Wilson has no financial relationships with companies related to this material. 

There is no cure for major neurocognitive disorder (MND), but several medications mitigate the progression of cognitive and functional decline.