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Clinical Update

A Spotlight on Two Emerging Nootropics

February 10, 2024
Jeremy Weleff, DO., Akhil Anand, MD., and Julian J. Raffoul, MD, PhD.
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Jeremy Weleff, DO. Yale School of Medicine, New Haven, CT; Cleveland Clinic, Cleveland, OH. Akhil Anand, MD. Cleveland Clinic, Cleveland, OH. Julian J. Raffoul, MD, PhD. Vanderbilt University Medical Center, Nashville, TN.

Dr. Weleff, Dr. Anand, and Dr. Raffoul have no financial relationships with companies related to this material.

Nootropics are a broad class of medications encompassing many different mechanisms of action that are marketed as cognitive enhancers. Not only do most nootropics lack evidence of efficacy, but some can have dangerous side effects and addictive potential. Here, we discuss some of the most concerning nootropics being widely used today.


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Research Update

Extended-Release Buprenorphine for Opioid Use Disorder in Correctional Settings

February 1, 2024
Eli Neustadter, MD, MSc.
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Eli Neustadter, MD, MSc. Dr. Neustadter has no financial relationships with companies related to this material.

Incarcerated individuals with opioid use disorder are at an especially heightened risk of adverse outcomes.  The period immediately following release is a particularly vulnerable time, with a much elevated risk of fatal overdose. In this study, investigators report on the use of extended-release injectable buprenorphine in a correctional setting.


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Research Update

Deep Brain Stimulation for Severe Alcohol Use Disorder

February 1, 2024
Maryam Soltani, MD, PhD.
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Maryam Soltani, MD, PhD. Dr. Soltani has no financial relationships with companies related to this material.

Despite its high prevalence, morbidity, and mortality, our treatment options for alcohol use disorder are limited. Severe alcohol use disorder can be especially challenging to treat. Here, researchers demonstrate the efficacy and feasibility of a novel treatment option: deep brain stimulation.


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Expert Q&A

Evaluating and Treating Patients With Problematic Sexual Behaviors

February 1, 2024
Amos Turner, MD.
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

QA2_Amos Turner Photo.jpegAmos Turner, MD.

Assistant professor of clinical psychiatry, Yale School of Medicine, New Haven, CT.

Dr. Turner has no financial relationships with companies related to this material.

Sexual addictions are rarely discussed with patients, even among addiction specialists. Societal taboos, social norms, and stigma can make it difficult for patients to discuss sexual issues with their providers. In this interview, Dr. Turner gives us tips in history gathering and covers what you need to know about diagnosis and treatment.


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Expert Q&A

Diagnosis and Treatment of Gambling Addiction

February 1, 2024
Timothy Fong, MD.
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

QA1_Timothy Fong headshot.pngTimothy Fong, MD. 

Clinical Professor of Psychiatry and Biobehavioral Sciences; Co-Director, Gambling Studies Program; David Geffen School of Medicine at UCLA, Los Angeles, CA.

Dr. Fong receives research support from Connections in Recovery. Relevant financial relationships listed for the author have been mitigated.

Gambling disorder is much more prevalent than many providers realize, and it is a condition that is rarely screened for, let alone treated, by mental health professionals. Here, Dr. Fong reviews the topic, walks us through how to take a good gambling history, make a diagnosis, and how to provide the best treatment.


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Clinical Update

Food Addiction and Related Disorders

February 1, 2024
Heidi Moawad, MD and Noah Capurso, MD, MHS
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Heidi Moawad, MD. Clinical assistant professor, Case Western Reserve School of Medicine, Cleveland, OH.

Noah Capurso, MD, MHS. Assistant professor of psychiatry, Yale University, New Haven, CT; Editor-in-Chief, The Carlat Addiction Treatment Report.

Dr. Moawad and Dr. Capurso have no financial relationships with companies related to this material.

Often lumped in with binge-eating disorder, food addiction is an emerging concept in the field of behavioral addictions.


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CME Post-Test, Benzodiazepines, CATR, October/November/December 2023

October 31, 2023
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

By successfully completing the test you will be awarded a certificate for 2 CME credit.


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Research Update

Perinatal MOUD Use and Infant Discharge to Biological Parents

October 31, 2023
Destiny Pegram, MD
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Destiny Pegram, MD. Dr. Pegram has no financial relationships with companies related to this material.

Pregnant patients with OUD may be reluctant to reveal their substance use for fear of losing their baby if reported to Child Protective Services. But this recent study shows that pregnant patients receiving medication treatment for OUD were more likely to leave the hospital with their baby than patients not receiving treatment.


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Research Update

Can Psilocybin Treat Alcohol Use Disorder?

October 31, 2023
Aniruddha Deka, MD
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Aniruddha Deka, MD. Dr. Deka has no financial relationships with companies related to this material. 

Recent preliminary research reveals that psilocybin helped participants with alcohol use disorder cut back on drinking. Dive in to discover how this psychedelic compound might offer hope for patients who have found other current treatments ineffective.


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Clinical Update

Xylazine: An Emerging Threat in the Opioid Overdose Epidemic

October 31, 2023
Roberto Sanchez, MD and Noah Capurso, MD
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Roberto Sanchez, MD. Addiction psychiatry fellow, Yale University School of Medicine, New Haven, CT.

Noah Capurso, MD, MHS. Assistant professor of psychiatry, Yale University, New Haven, CT; Editor-in-Chief, The Carlat Addiction Treatment Report.

Dr. Sanchez and Dr. Capurso have no financial relationships with companies related to this material.

Xylazine is the latest contaminant being found in the American illicit drug supply. A non-opioid itself, xylazine is usually combined with fentanyl, with which it has synergistic sedative effects. Patients using xylazine can have profound levels of sedation and develop severe peripheral wounds. In this article, we discuss xylazine essentials and cover harm reduction strategies to help keep your patients safe.


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