David Osser, MD

Expert Q&A

Psychopharmacology for PTSD

April 1, 2026

Associate Professor of Psychiatry, Harvard Medical School, Brockton Veteran’s Administration Medical Center, Brockton, MA. Dr. Osser has no financial relationships with companies related to this material.

David Osser, MD, explains why treating sleep first is central to PTSD care—and how to use prazosin effectively despite lingering controversies.

The Psychopharmacology Algorithm Project

March 30, 2020

David Osser, MD

David Osser, MD

General Editor of the Psychopharmacology Algorithm Project at the Harvard South Shore Psychiatry Residency Training Program and Associate Professor of Psychiatry at Harvard University. Dr. Osser has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Dr. Osser set out to develop a psychopharmacology algorithm that actually changes practice. He speaks to us on antidepressants in bipolar, psychoses that don’t need antipsychotics, and his top picks for bipolar mania, bipolar depression, and unipolar depression.

Topics in the Diagnosis and Treatment of PTSD

June 1, 2007

David Osser, MD

David N. Osser, MD. Associate Professor of Psychiatry, Harvard Medical School, Brockton Veteran’s Administration Medical Center, Brockton, Massachusetts.

Dr. Osser has disclosed that he has no significant relationships with or financial interests in any commercial companies pertaining to this educational activity.

Dr. Osser, as an attending psychiatrist at a VA unit in which you evaluate many patients with PTSD, how do you typically approach establishing a valid and reliable diagnosis of PTSD in your patients?