fda-warnings - Page 1 | CARLAT PUBLISHING

A Potentially Lethal Side Effect You Probably Never Heard Of

May 7, 2020

Chris Aiken, MD. Editor-in-Chief of TCPR. Practicing psychiatrist, Winston-Salem, NC. Dr. Aiken has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

The FDA recently raised alerts about a potentially fatal side effect on clozapine that’s causing more fatalities than neutropenia. It’s constipation, and the problem extends to a few other psychotropics as well. In this article, a three step, evidence-based algorithm for managing it.

Varenicline and Bupropion: Soaring Again With EAGLES?

November 22, 2019

Nicholas Rosenlicht, MD.

Nicholas Rosenlicht, MD. Dr. Rosenlicht has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

This research update unpacks the details behind the landmark “EAGLES” trial (Evaluating Adverse Events in a Global Smoking Cessation Study), which led to the removal of the varenicline black box warning.

A New Contraindication for Ambien and the Z-Hypnotics

August 30, 2019

Chris Aiken, MD Talia Puzantian, PharmD, BCPP

Chris Aiken, MD Talia Puzantian, PharmD, BCPP Dr. Aiken and Dr. Puzantian have disclosed that they have no relevant financial or other interests in any commercial companies pertaining to this educational activity.

The FDA rarely issues absolute contraindications, but that’s where their language is tilting in a new warning on Z-Hypnotics. We look at the data behind their decision and offer six tips for safer prescribing of sleep medications.