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Clinical Guidance

Table: Psychiatric Medications in Pregnancy and Lactation

April 24, 2026

Victoria Hendrick, MD and Daniel Carlat, MD

Dr. Hendrick and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Table: Psychiatric Medications in Pregnancy and Lactation

Fact Sheet

Depression in Pregnancy: Diagnosis and Treatment

April 24, 2026

Victoria Hendrick, MD and Daniel Carlat, MD

Dr. Hendrick and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Prenatal depression is common, affecting 10%–15% of pregnant patients.

Expert Q&A

Perinatal Mental Health

January 28, 2026

Amritha Bhat, MBBS, MD, MPH

Amritha Bhat, MBBS, MD, MPH. Associate Professor, Department of Psychiatry and Behavioral Sciences, University of Washington.

Dr. Bhat has no financial relationships with companies related to this material.

We take a close look at the new FDA panel on antidepressants in pregnancy, treatment guidelines for postpartum psychosis, and the role of zuranolone.

Mood Disorders in Pregnancy, Postpartum, and Breastfeeding

August 13, 2025

Daniel Carlat, MD

What do you say when a pregnant patient asks if her medication will hurt the baby?

You have 15 minutes. And you’re not entirely sure.

Pregnancy Doesn’t Protect Against Depression

August 12, 2025

Daniel Carlat, MD

Pregnancy is wonderful. But don't buy the myth that it protects against depression.

Clinical Guidance

Neonatal Opioid Withdrawal Syndrome: Recognition and Management

January 1, 2025

Noah Capurso, MD, MHS, Talia Puzantian, PharmD, BCPP, and Daniel Carlat, MD

Dr. Capurso, Dr. Puzantian, and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Neonatal opioid withdrawal syndrome (NOWS), sometimes used interchangeably with the term neonatal abstinence syndrome (NAS), results from prenatal opioid exposure.

Clinical Guidance

Managing Opioid Use Disorder in Pregnant People

January 1, 2025

Noah Capurso, MD, MHS, Talia Puzantian, PharmD, BCPP, and Daniel Carlat, MD

Dr. Capurso, Dr. Puzantian, and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Rates of opioid use disorder (OUD) and overdose deaths during pregnancy have skyrocketed in recent years.

Clinical Guidance

Treatment of Bipolar Disorder in Pregnant and Postpartum Women - A Review Sheet

November 19, 2024

Victoria Hendrick, MD

Dr. Hendrick has no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Begin preparation at least six months before conception to ensure stability, switch to safer medications, and manage psychosocial stressors.

Research Update

Buprenorphine Versus Methadone for Opioid Use Disorder in Pregnancy

July 1, 2024

Richard Moldawsky, MD

Richard Moldawsky, MD. Dr. Moldawsky has no financial relationships with companies related to this material.

Buprenorphine and methadone are both first-line treatments for opioid use disorder during pregnancy. Though this recommendation has been long-standing, it is based on a rather small study that is nearly 15 years old. In the current study, researchers revisit the question of how best to treat opioid use disorder during pregnancy with a large observational cohort study.

Expert Q&A

Pregnancy, Addiction, and the Law

July 1, 2024

Elisabeth Johnson, PhD, FNP-BC, CARN-AP, LCAS

Elisabeth Johnson, PhD, FNP-BC, CARN-AP, LCAS.

Division Director, UNC Horizons; Clinical Assistant Professor,UNC-Chapel Hill, Carrboro, NC.

Dr. Johnson has no financial relationships with companies related to this material.

Dr. Johnson tells us all about Child Protective Services and how they work with pregnant patients who use substances. In this interview, she reviews the role of medical and mental health providers in the care of pregnant patients with addictive disorders and their legal obligations. She also provides tips for discussing these sensitive matters with your patients.