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The Carlat Psychiatry Report

Research in Psychiatry (July/August) | 2014

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Research Domain Criteria (RDoC)

July 1, 2014

Bruce Cuthbert, PhD, the head of the NIMH’s new Research Domain Criteria (RDoC) program, explains how this new way of funding and conducting research in psychiatry is revolutionizing the field. Read More

New Study Supports Cardiac Safety of SSRIs in Pregnancy

July 1, 2014

Concerns about the safety of psychiatric medications during pregnancy are common among psychiatrists and patients alike. In many cases, one must weigh the risks of a medication to mother or child against the risks inherent in untreated mental illness. Recent research, however, lends support to the growing data about the safety of antidepressant medications in pregnancy. Read More

Worksheet: Finding Associations in the Data

July 1, 2014

Documents:

Investigating Bias in Research

July 1, 2014

Rebecca Twersky-Kengmana, MD

It’s important to understand what bias is not. Bias is not fraud, as it does not involve intentional prejudice. Bias is also not random error, which creates deviation in results strictly by chance, and can be mitigated with a large enough study sample. Put simply, bias has to do with the unintentional skewing of results due to human failings such as poor trial design or unconscious wishes for desirable outcomes. Read More

How to Read a Research Article

July 1, 2014

Joshua Sonkiss, MD

As a physician, you’re expected to practice evidence-based medicine. But how can anyone keep up with the latest research? Read More

Overview of the FDA Drug Approval Process

July 1, 2014

Glen Spielmans, PhD

After a psychiatric drug is approved by the Food and Drug Administration (FDA), a marketing juggernaut often follows, trying to convince us that the newly approved drug offers substantial benefits for treating a mental disorder. But how does the FDA determine whether to approve a drug? What follows is a breakdown of the process. Read More