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Home » Newsletters » The Carlat Psychiatry Report
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The Carlat Psychiatry Report

Neuropsychiatry (November/December) | 2025

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Learning Objectives, Neuropsychiatry, TCPR, November/December 2025

November 1, 2025

After reading these articles, you should be able to…

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New Combination Therapies

November 1, 2025
David Liebers, MD

With few new psychiatric drugs on the horizon, researchers are turning to creative combinations of old standbys to tackle tough cases of addiction and beyond.

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The Diagnostic Expansion of ADHD, Part 1

November 1, 2025
C. Thomas Gualtieri, MD

How did we get from “math pills” in 1937 to today’s “ADHD boom”? Dr. Gualtieri traces the surprising history—and overreach—of stimulant use. 

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The Diagnostic Expansion of ADHD, Part 2

November 1, 2025
C. Thomas Gualtieri, MD

Stimulants boost energy, but often mislead. Dr. Gualtieri unpacks misdiagnosis, anxiety, and why careful differential diagnosis matters more than ever.

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Dopamine Partial Agonists for Treatment-Resistant Depression

November 1, 2025
Alla Alexander, MD

Low doses of aripiprazole, brexpiprazole, or cariprazine offer modest but meaningful gains for TRD.

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Zuranolone Not Helpful for Major Depression

November 1, 2025
Dee Rapposelli

Zuranolone shows modest short-term benefit in major depression, but results fall short of meaningful clinical impact

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Celecoxib for Postpartum Depression

November 1, 2025
Sarah Azarchi, MD

Postpartum depression (PPD) affects 12% of mothers and takes a toll on infant and family health. 

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Repurposing Semaglutide and Liraglutide for Alcohol Use Disorder

November 1, 2025
Anna Vinter, MD

Alcohol use disorder (AUD) is notoriously difficult to treat, with pharmacological options often underutilized or only modestly effective. But what if a medication already used for diabetes and obesity could help?

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Editor-in-Chief
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Chris Aiken, MD
Dr. Aiken is the Editor in Chief of The Carlat Psychiatry Report; director of the Mood Treatment Center in North Carolina, where he maintains a private practice combining medication and therapy along with evidence-based complementary and alternative treatments; and Assistant Professor NYU Langone Department of Psychiatry. He has worked as a research assistant at the NIMH and a sub-investigator on clinical trials, and conducts research on a shoestring budget out of his private practice. Follow him on Twitter and find him on LinkedIn.

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