Using Medical Management in Treating Opioid Use Disorder
The Carlat Addiction Treatment Report, Volume 6, Number 8, November 2018
Andrew Saxon, MD
Professor, Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine and Director, Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Health Care System, Seattle, WA. Chair, Council on Addiction Psychiatry.
Dr. Saxon has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
To set the stage for understanding medical management, we need to go back about 20 years to the inception of the landmark COMBINE Study. This study was a very large clinical trial for alcohol use disorder (AUD) that compared naltrexone, acamprosate, and their combination, and also looked at two behavioral interventions.